Results 161 to 170 of about 6,056,925 (239)

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Formal Synthesis of <i>Ortho</i>-Cyanated <i>N</i>-Heterocycles via Direct, Metal-Free Cyanation of <i>N</i>-Oxides Under Benign Conditions. [PDF]

Molecules
Xiao H, Wufuer R, Wang D.
europepmc   +1 more source

ÐÑÑледование влиÑÐ½Ð¸Ñ ÑÑÑÑкÑÑÑÑ Ð¸Ð½Ð²ÐµÑÑиÑионного поÑÑÑÐµÐ»Ñ Ð½ÐµÐ³Ð¾ÑÑдаÑÑÑвеннÑÑ Ð¿ÐµÐ½ÑионнÑÑ Ñондов по обÑзаÑелÑÐ½Ð¾Ð¼Ñ Ð¿ÐµÐ½ÑÐ¸Ð¾Ð½Ð½Ð¾Ð¼Ñ ÑÑÑÐ°Ñ Ð¾Ð²Ð°Ð½Ð¸Ñ Ð½Ð° Ð´Ð¾Ñ Ð¾Ð´Ð½Ð¾ÑÑÑ Ð¸Ð½Ð²ÐµÑÑиÑий

, 2016
Наталья Игоревна Белясова
openalex   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Impact of vitamin D non-reimbursement policy on therapy discontinuation in the general and rheumatic population in the Netherlands: a cross-sectional study. [PDF]

BMJ Open
Singh A, Huiskes VJB, van den Bemt BJF, van Ameijden H, Nurmohamed MT, Spijkers KM, Vervloet M, Brabers AEM.   +7 more
europepmc   +1 more source

ХХV ÐÑжнаÑÐ¾Ð´Ð½Ð°Ñ Ð½Ð°Ð²ÑÐºÐ¾Ð²Ð°Ñ ÐºÐ°Ð½ÑеÑÑнÑÑÑ âÐелаÑÑÑка-полÑÑкÑÑ Ð¼Ð¾ÑнÑÑ, лÑÑаÑаÑÑÑнÑÑ, гÑÑÑаÑÑÑнÑÑ Ñ ÐºÑлÑÑÑÑнÑÑ ÑÑвÑзÑâ: Ñ Ð³Ð¾Ð½Ð°Ñ Ð¿ÑаÑеÑаÑа ÐлÑжбеÑÑ CмÑлковай

, 2016
Maryna Swistunowa
openalex   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Vitamin D Deficiency as a Risk Factor for Onset and Recurrence of Sudden Sensorineural Hearing Loss: A Prospective Cohort Study With Age-Specific Analysis. [PDF]

Food Sci Nutr
Hui Q, Xiang T, Qinglan X, Shuowei Y, Mengshi C, Qin X, Hongyin L, Juntao Y, Yunping F.   +8 more
europepmc   +1 more source