Results 181 to 190 of about 5,636,365 (246)

What drives clinic follow-up after traumatic spinal injury? An observational cohort study from Tanzania. [PDF]

BMJ Open
Ikwuegbuenyi CA, Woodfield J, Sabas RR, Inzerillo S, Willett N, Cadieux M, Zuckerman SL, Waterkeyn F, Mangat HS, Shabani HK, Härtl R.   +10 more
europepmc   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Evaluation of disproportionately enlarged subarachnoid-space hydrocephalus in progressive supranuclear palsy. [PDF]

Brain Commun
Fu MH, Gunter JL, Satoh R, Gatto RG, Ali F, Clark HM, Stierwalt JA, Machulda MM, Stephens YC, Youssef H, Thu Pham NT, Jack CR, Lowe VJ, Josephs KA, Whitwell JL.   +14 more
europepmc   +1 more source

ТермокаталитичеÑкий гидрогенолиз горючих Ñланцев

, 2012
Zhaksyntay Kairbekov, V.S. Yemelyanova, A. S. Maloletnev, Bedelzhan Baizhomartov   +3 more
openalex  

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

FEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei, Zhanbiao Liu, Jingjing Shi, Qian Jin, Wenqian Chen, Xuejun Chen, Liqin Li, Hui Chen   +7 more
wiley   +1 more source

Vitamin D Levels and Prevalence of Vitamin D Deficiency in Turkish Women According to Regions and Age Groups. [PDF]

Med Sci Monit
Semiz A, Özbay K, Şanlıkan F, Yılanlıoğlu NC, Arısoy R, Tekkeşin N.   +5 more
europepmc   +1 more source

Cинтез в пламени Ñупергидрофобной Ñажи и ее применение

, 2013
Meruert Nazhipkyzy, M. Auyelkhankyzy, B. Lesbayev, З. А. Мансуров, A. Amantayeva, A. Iskakova, Yelchin Aliyev, A. Zhaparova   +7 more
openalex   +1 more source

Downregulation of O‐GlcNAcylation enhances etoposide‐induced p53‐mediated apoptosis in HepG2 human liver cancer cells

FEBS Open Bio, EarlyView.
Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee, Gi‐Bang Koo, Jihye Park, Byung‐Cheol Han, Mijin Kwon, Seung‐Ho Lee   +5 more
wiley   +1 more source