Workflow of a high‐throughput technology for epigenotyping of differentially methylated CpGs in specific regions of the genome. The protocol works with small amounts of DNA extracted from blood or semen. The protocol consists of both enzymatic conversion of unmethylated cytosines and capture by hybridization with a custom panel.
Nathalie Iannuccelli+4 more
wiley +1 more source
Nitrogen deficiency impacts growth and modulates carbon metabolism in maize. [PDF]
Amoah JN, Keitel C, Kaiser BN.
europepmc +1 more source
Osmotic pressure‐induced calcium response states
Acute hypotonic stress triggers distinct calcium response patterns in HEK293T cells. These signals originate from the endoplasmic reticulum via RyR2 and propagate to neighboring cells through gap junctions. This result highlights a novel calcium‐dependent mechanism underlying the intracellular and intercellular response to osmotic pressure.
Zidan Gao+2 more
wiley +1 more source
Relationship between left ventricular wall stress and cardiac remodelling post-TAVR and MitraClip. [PDF]
Papapostolou S+10 more
europepmc +1 more source
The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions
Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh+2 more
wiley +1 more source
Who Needs Endoscopic Removal of Food Residue From the Esophagus Before Peroral Endoscopic Myotomy for Esophageal Achalasia and Esophagogastric Junction Outflow Obstruction? [PDF]
Kaizuka M+12 more
europepmc +1 more source
Cerebral glucose delivery, transport and metabolism: Theory and modeling using four, three, and two tissue compartments. [PDF]
Seidemo A+5 more
europepmc +1 more source
Ongoing circulation of emerging tick-borne viruses in Poland, Eastern Europe. [PDF]
Ergunay K+13 more
europepmc +1 more source
Author Correction: hsa_circ_0008305 facilitates the malignant progression of hepatocellular carcinoma by regulating AKR1C3 expression and sponging miR-379-5p. [PDF]
Huang S+5 more
europepmc +1 more source