Results 41 to 50 of about 6,424,268 (248)
N,N-Dimethyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine monohydrate
IUCrData, 2018 The asymmetric unit of the title compound, C7H9N5·H2O, consists of two formula units differing slightly in the orientation of the dimethylamino groups. In the crystal, a combination of O—H...N and N—H...O hydrogen bonds involving the water molecules of ...
Mohamed El Hafi +5 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
, 2018 The aim of this study was to evaluate the central obesity, which is a main characteristic of Cushing's syndrome (CS), with dual-energy x-ray absorptiometry (DXA) and to determine DXA indexes that precisely differentiate CS from non CS obese women.
ШубеÑка-Стратрова (Shubeska Stratrova), Славица (Slavica) +1 more
core
On α′-effects from D-branes in 4d N $$ \mathcal{N} $$ = 1
Journal of High Energy Physics, 2020 In this work we study type IIB Calabi-Yau orientifold compactifications in the presence of space-time filling D7-branes and O7-planes. In particular, we conclude that α′2 g s -corrections to their DBI actions lead to a modification of the four ...
Matthias Weissenbacher
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Морбили во фаза на задолжителна вакцинација
, 2016 The conclusion of the authors is that, beside the vaccination, measles are still present in our pathology.The most frequent and the hardest complications are respiratory ones as bronchopneumonia, pneumonia, bronchitis, bronchiolitis, stomatitis, and ...
Караџов (Karadzhov), Зоран (Zoran) +2 more
core
N-[4-(β-d-Allopyranosyloxy)benzylidene]methylamine
Acta Crystallographica Section E, 2009 The title compound, C14H19NO6, was synthesized by the condensation reaction between hecilid (4-formylphenl-β-d-allopyranoside) and methylamine in methanol.
Shu-Fan Yin +4 more
doaj +1 more source
Forest Gothic of D. N. Mamin-Sibiryak
Филологический класс, 2023 The article analyzes a micro detail of D. N. Mamin-Sibiryak’s landscape poetics: the metaphorical epithet Gothic in descriptions of coniferous forests of the Urals, its semantic role, and genesis.
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source