Results 91 to 100 of about 6,167,274 (252)
Anti-N-Methyl-D-Aspartate Receptor Encephalitis
Pediatric Neurology Briefs, 2013 Investigators at Universities of Barcelona, Pennsylvania, Oviedo, and Valencia, and the Spanish NMDAR Encephalitis Work Group report the clinical features of 20 pediatric patients with anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis seen in a ...
J Gordon Millichap
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Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
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Anti-N-Methyl-d-Aspartate Receptor Encephalitis
Pediatrics and Neonatology, 2011 Anti-N-methyl-d-aspartate (NMDA) receptor encephalitis is a treatment-responsive encephalitis associated with anti-NMDA receptor antibodies, which bind to the NR1/NR2 heteromers of the NMDA receptors.
Te-Yu Hung, Ning-Hui Foo, Ming-Chi Lai
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Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Langues & CulturesAmagrad-a d asumer n usenfar asensegman i uselmed d ulmad n temseɛraq deg tneɣrit n tmaziɣt. Tawsit-a n yinaw i yekkin ɣer tsekla tamensayt, timawit deg tuget, yella deg-s usmeskel seg temnaḍt ɣer tayeḍ. Asegzawal n usmeskel d ttawil n uḥraz n tgemmi-ya
Yacine MEZIANI
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
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N. A. Polevojaus laiškai S. D. Poltorackiui
Literatūra (Vilnius), 1966 Nikolajus Aleksejevičius Polevojus (1796–1846), žinomas „Maskvos telegrafo" redaktorius ir leidėjas, vienas iš žymesniųjų V. G. Belinskio pirmtakų, rusų XIX a. literatūroje buvo antidvarininkiškos literatūros kritikos pradininkas. Jis pradėjo
V. Salinka
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Плазма-ренинÑка активноÑÑ‚ кај нормотензивните (ÐТ), метакортикоидните (МК), Ñпонатнохипертензивните (СХ) и Ñпонтанохипертензивните "Stroke Prone" (SH-p) [PDF]
, 2017 The level of plasma rennin activity in normotensive (NTR), metacorticoide (MHR), spontaneous hypertensive (SHR) and spontaneous hypertensive stroke prone rats (SHR/SP) has been studied and the results presented in this report.Plasma rennin activity was ...
Петров (Petrov), Стојмир (Stojmir) +1 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
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