Results 121 to 130 of about 5,871,797 (300)

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

大阪市立自然史博物館館報32(平成18年度) [PDF]

open access: yes, 2017
市民参加による特別展 山西良平 1指定管理者の導入にあたって 山西良平 2展覧事業 3調査研究事業 9資料収集保管事業 18普及教育事業 28その他の事業 39庶務 ...

core   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

Razeyev D. N. I. Kant's teleology [PDF]

open access: yesКантовский сборник, 2011
Balanovsky, V. V.
doaj   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

Exact moduli spaces for N $$ \mathcal{N} $$ = 2, D = 5 freely acting orbifolds

open access: yesJournal of High Energy Physics
We use freely acting asymmetric orbifolds of type IIB string theory to construct a class of theories in five dimensions with eight supercharges whose moduli spaces for vector multiplets and hypermultiplets can be determined exactly.
George Gkountoumis   +2 more
doaj   +1 more source

Inference for a zero-inflated Conway-Maxwell-Poisson regression for clustered count data. [PDF]

open access: yes, 2016
This dissertation is directed toward developing a statistical methodology with applications of the Conway-Maxwell-Poisson (CMP) distribution (Conway, R. W., and Maxwell, W. L., 1962) to count data.
Choo-Wosoba, Hyoyoung
core   +1 more source

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