Results 171 to 180 of about 5,871,797 (300)

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

open access: yesMolecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova   +26 more
wiley   +1 more source

Timuzzla deg tmurt n Leqbayel (Lezzayer), gar umezruy d tgemmi: taddart n Yiḥiṭṭuṣen

open access: yesLangues & Cultures
Tazrawt-nneɣ tekcem di taɣult n tesnalest tadelsant, yes-s nezrew agraw anmetti n Yiḥiṭṭusen d yiḥeddaden-is s wayes-s i neɛreḍ ad d-nessegzi belli tanḍa d tmuzzla d yiwen n uneḍru anmetti amatu.
Massinissa SAIDANI
doaj  

Synthesis, Characterization, and Antimicrobial Evaluation of Some Novel Hydrazinecarbothioamides. [PDF]

open access: yesTurk J Pharm Sci
Dincel ED   +5 more
europepmc   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

open access: yesMolecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li   +12 more
wiley   +1 more source

Exploring Implicit Emotional Associations With Death in Patients With Current Suicidal Ideation: Results From Novel Attitude Implicit Association Tests for Suicide. [PDF]

open access: yesSuicide Life Threat Behav
Aschenbrenner LM   +9 more
europepmc   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

open access: yesMolecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi   +12 more
wiley   +1 more source

Discocelia Plataet Sp. n., a Small Incertae Sedis Cercozoan Flagellate. [PDF]

open access: yesJ Eukaryot Microbiol
Prokina K   +5 more
europepmc   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

open access: yesMolecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy