Results 111 to 120 of about 6,774,207 (248)
Two sucker babies with fibrosa cystic have been presented: in one of them the disease was severe with the lethal outcome, while the other baby could be successfully treated.
СпировÑки (Spirovski), Зоран (Zoran) +2 more
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Три Ñлучаи на Syndroma Willi Prader Labhardt во доенечка возраÑÑ‚ [PDF]
Authors presented three cases of Willi Prader Labhardt Syndroma whose cardinal symptoms are: psychomotor retardation, proportional obesity, hypogenitalism, a small bifrontal circumference, and carp-like mouth.During the pregnancy, children's mothers felt
Гордова-МуратовÑка (Gordova-Muratovska), ÐлекÑандра (Aleksandra) +2 more
core
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Радиоимунолошко одредување на нормални предпладневни вредноÑти на ÐЦТХ и кортизол во плазмата кај женÑки и машки иÑпитаници [PDF]
Basal levels of ACT and cortisol in the plasma show diurnal, menstrual and gravidities variations. Several authors have presented mean value with large deviations making difficulties in the clinical interpretation of the results.In order to get more real
Ðикодијевиќ (Nikodijevikj), Олга (Olga) +1 more
core
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
The levels of estradiol, progesterone and gonadotropins were determined by radioimmunoassay in 8 healthy women, aging 18-22 years, with histories of regular menstruation.
ДеловÑка (Delovska), ВеÑна (Vesna) +1 more
core

