Results 141 to 150 of about 6,175,603 (300)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Ðндроид/нозе и нозе/труп индекÑи одредени Ñо абÑорпциметрија Ñо двојно-енергетÑки x-зраци кај Кушинг и не-Кушинг здебелени жени [PDF]
, 2018 The aim of this study was to evaluate the central obesity, which is a main characteristic of Cushing's syndrome (CS), with dual-energy x-ray absorptiometry (DXA) and to determine DXA indexes that precisely differentiate CS from non CS obese women.
ТодоровÑка (Todorovska), Лидија (Lidija) +1 more
core +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Ticraḍ, gar usemres d wazal n yizamulen i d-mmalent
UssnanThis contribution aims to describe the practice of tattooing in some Amazigh regions. It tries to list the different techniques, the actors plus the means used to succeed in this practice which has a high value in the society.
Ourida AISSOU
doaj
ИÑпитување на кинетиката на радиоактивно обележен кортизол кај Ñтаорци [PDF]
, 2016 Kinetics of tritium labeled coгtisol was performed in control rats, rats treated with Synacthen Depot and rats treated with Dexamethason i.m. Rats were injected with 2 microCuri directly into the lateral tail vein and timed samples were collected by ...
СпироÑки (Spiroski), Мирко (Mirko) +2 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
The DIA program ensured the growth of lending to priority sectors of the economy - by 64.5% [PDF]
, 2018 Original title in Russian is ПроÐóрамма ÐСВ обеÑпечила роÑÑ‚ ÐºÑ€ÐµÐ´Ð¸Ñ‚Ð¾Ð²Ð°Ð½Ð¸Ñ Ð¿Ñ€Ð¸Ð¾Ñ€Ð¸Ñ‚ÐµÑ‚Ð½Ñ‹Ñ… отраÑлей Ñкономики – на 64 ...
Vilenovich, Perchyan Andrey
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source