Results 231 to 240 of about 6,774,207 (248)

Dynamic perioperative thrombo-inflammatory biomarkers correlate with early functional outcomes after mechanical thrombectomy for acute ischemic stroke. [PDF]

Front Neurosci
Liu P, Chen Y, Shen D, Wang T, Han X, Shen D, Sun H, Wang J, Wu H, Wang T.   +9 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Sequence Inversion Dictates the Antiproliferative Activity of Bidirectional Tryptophan-Containing Dipeptide Libraries. [PDF]

J Pept Sci
Díaz JB, Khan AN, González-Bakker A, Padrón JM.   +3 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Discovery of 2-(2-Benzoyl-5-Phenyl-<i>1H</i>-Imidazol-1-Yl) Derivatives as Inhibitors of Factor XIIa. [PDF]

ChemistrySelect
Al-Horani RA, Silva SM, Rajam JMT, Rashid R, Chouhan R, Verma V, Afosah DK, Goyal N.   +7 more
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Nitrogen deposition does not alter the temperate forest soil carbon pool: A 14-y experiment on varied nitrogen fertilization. [PDF]

Proc Natl Acad Sci U S A
Zhang Y, Hobbie SE, Schlesinger WH, Sun T.   +3 more
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Retention of graphene-reinforced polymethyl methacrylate crowns bonded to titanium-base abutments: an exploratory in vitro study. [PDF]

BDJ Open
Prats Sisquella B, A Peeva N, Torné-Durán S, Ascaso-Terren C, Escuin-Henar T.   +4 more
europepmc   +1 more source