Results 111 to 120 of about 6,331,097 (235)
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.Stavros Azinas, Marta Carroniwiley +1 more sourcepH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...Xuelang Mu, Ampon Sae Her, Tamir Gonenwiley +1 more sourceThe CMS experiment at the CERN LHC
, 2008 S. Chatrchyan, G. Hmayakyan, V. Khachatryan, A. Sirunyan, W. Adam, T. Bauer, T. Bergauer, H. Bergauer, M. Dragicevic, J. Erö, M. Friedl, R. Frühwirth, V. Ghete, P. Glaser, C. Hartl, N. Hoermann, J. Hrubec, S. Hänsel, M. Jeitler, K. Kastner, M. Krammer, M. Markytan, I. Mikulec, B. Neuherz, Tobias Nöbauer, M. Oberegger, M. Padrta, M. Pernicka, P. Porth, H. Rohringer, S. Schmid, T. Schreiner, R. Stark, H. Steininger, J. Strauss, A. Taurok, D. Uhl, W. Waltenberger, G. Walzel, E. Widl, C. Wulz, V. Petrov, V. Prosolovich, V. Chekhovsky, O. Dvornikov, I. Emeliantchik, A. Litomin, V. Makarenko, I. Marfin, V. Mossolov, N. Shumeiko, A. Solin, R. Stefanovitch, S. Gonzalez, A. Tikhonov, A. Fedorov, M. Korzhik, O. Missevitch, R. Zuyeuski, W. Beaumont, M. Cardaci, E. D. Langhe, E. Wolf, E. Delmeire, S. Ochesanu, M. Tasevsky, P. Mechelen, J. D’Hondt, S. D. Weirdt, O. Devroede, R. Goorens, S. Hannaert, J. Heyninck, J. Maes, M. Mozer, S. Tavernier, W. Doninck, L. V. Lancker, P. Mulders, I. Villella, C. Wastiels, C. Yu, O. Bouhali, O. Charaf, B. Clerbaux, P. D. Harenne, G. Lentdecker, J. Dewulf, S. Elgammal, R. Gindroz, G. Hammad, T. Mahmoud, L. Neukermans, M. Pins, R. Pins, S. Rugovac, J. Stefanescu, V. Sundararajan, C. Velde, P. Vanlaer, J. Wickens, M. Tytgat, S. Assouak, J. Bonnet, G. Bruno, J. Caudron, B. D. Callatay, De Jeneret, S. Visscher, P. Demin, D. Favart, C. Felix, B. Florins, E. Forton, A. Giammanco, G. Grégoire, M. Jonckman, D. Kcira, T. Keutgen, V. Lemaitre, D. Michotte, O. Militaru, S. Ovyn, T. Pierzchala, K. Piotrzkowski, V. Roberfroid, X. Rouby, N. Schul, O. Aa, N. Beliy, E. Daubie, P. Herquet, G. Alves, M. Pol, M. Souza, M. Vaz, D. Damiao, V. Oguri, A. Santoro, A. Sznajder, E. Gregores, R. Iope, S. Novaes, T. Tomei, T. Anguelov, G. Antchev, I. Atanasov, J. Damgov, N. Darmenov, L. Dimitrov, V. Genchev, P. Iaydjiev, A. Marinov, S. Piperov, S. Stoykova, G. Sultanov, R. Trayanov, I. Vankov, C. Cheshkov, A. Dimitrov, M. Dyulendarova, I. Glushkov, V. Kozhuharov, L. Litov, M. Makariev, E. Marinova, S. Markov, M. Mateev, I. Nasteva, B. Pavlov, P. Petev, P. Petkov, V. Spassov, Z. Toteva, V. Velev, V. Verguilov, J. Bian, Guo-ming Chen, He-Sheng Chen, M. Chen, C. Jiang, B. Liu, X. Shen, H. Sun, J. Tao, Jian Wang, Mingming Yang, Zhiqin Zhang, W. Zhao, H. Zhuang, Y. Ban, J. Cai, Y. Ge, S. Liu, H. Liu, L. Liu, S. Qian, Q. Wang, Z. Xue, Zongchang Yang, Y. Ye, J. Ying, P. Li, J. Liao, Z. Xue, D. Yan, H. Yuan, C. Montoya, J. Sanabria, N. Godinovic, I. Puljak, I. Sorić, Z. Antunović, M. Dželalija, K. Marasovic, V. Brigljevic, K. Kadija, S. Morović, R. Fereos, C. Nicolaou, A. Papadakis, F. Ptochos, P. Razis, D. Tsiakkouri, Z. Zinonos, A. Hektor, M. Kadastik, K. Kannike, É. Lippmaa, M. Müntel, M. Raidal, L. Rebane, P. Aarnio, E. Anttila, K. Banzuzi, P. Bulteau, S. Czellár, N. Eiden, C. Eklund, P. Engstrom, A. Heikkinen, A. Honkanen, J. Härkönen, V. Karimäki, H. Katajisto, R. Kinnunen, J. Klem, J. Kortesmaa, M. Kotamäki, A. Kuronen, T. Lampén, K. Lassila-Perini, V. Lefébure, S. Lehti, T. Lindén, P. Luukka, S. Michal, F. Brígido, T. Mäenpää, T. Nyman, J. Nysten, E. Pietarinen, K. Skog, K. Tammi, E. Tuominen, J. Tuominiemi, D. Ungaro, T. Vanhala, L. Wendland, C. Williams, M. Iskanius, A. Korpela, G. Polese, T. Tuuva, G. Bassompierre, A. Bazan, P. David, J. Ditta, G. Drobychev, N. Fouque, J. Guillaud, V. Hermel, A. Karneyeu, T. L. Flour, S. Lieunard, M. Maire, P. Mendiburu, P. Nédélec, J. Peigneux, M. Schneegans, D. Sillou, J. Vialle, M. Anfreville, J. Bard, P. Besson, E. Bougamont, M. Boyer, P. Brédy, R. Chipaux, M. Dejardin, D. Denegri, J. Descamps, B. Fabbro, J. Faure, S. Ganjour, F. Gentit, A. Givernaud, P. Gras, G. H. Monchenault, P. Jarry, C. Jeanney, F. Kircher, M. Lemaire, Y. Lemoigne, B. Levésy, E. Locci, J. Lottin, I. Mandjavidze, M. Mur, J. Pansart, A. Payn, J. Rander, J. Reymond, J. Rolquin, F. Rondeaux, A. Rosowsky, J. Rousse, Z. Sun, J. Tartas, A. Lysebetten, P. Venault, P. Verrecchia, M. Anduze, J. Badier, S. Baffioni, M. Bercher, C. Bernet, U. Berthon, J. Bourotte, A. Busata, P. Busson, M. Cerutti, D. Chamont, C. Charlot, C. Collard, A. Debraine, D. Decotigny, L. Dobrzyński, O. Ferreira, Y. Geerebaert, J. Gilly, C. Gregory, L. Riveros, M. Haguenauer, A. Karar, B. Koblitz, D. Lecouturier, A. Mathieu, G. Milleret, P. Miné, P. Paganini, P. Poilleux, N. Pukhaeva, N. Regnault, T. Romanteau, I. Semeniouk, Y. Sirois, C. Thiebaux, J. Vanel, A. Zabi, J. Agram, A. Albert, L. Anckenmann, J. Andrea, F. Anstotz, A. Bergdolt, J. Berst, R. Blaes, D. Bloch, J. Brom, J. Cailleret, F. Charles, E. Christophel, G. Claus, J. Coffin, C. Colledani, J. Croix, E. Dangelser, N. Dick, F. Didierjean, F. Drouhin, W. Duliński, J. Ernenwein, R. Fang, J. Fontaine, G. Gaudiot, W. Geist, D. Gelé, T. Goeltzenlichter, U. Goerlach, P. Graehling, L. Gross, C. Hu, J. M. Helleboid, T. Henkes, M. Hoffer, C. Hoffmann, J. Hosselet, L. Houchu, Y. Hu, D. Huss, C. Illinger, F. Jeanneau, P. Juillot, T. Kachelhoffer, M. Kapp, H. Kettunen, L. Ayat, A. Bihan, A. Lounis, C. Maazouzi, V. Mack, P. Majewski, D. Mangeol, J. Michel, S. Moreau, C. Olivetto, A. Pallarès, Y. Patois, P. P. vorio, C. Racca, Y. Riahi, I. Ripp-Baudot, P. Schmitt, J. Schunck, G. Schuster, B. Schwaller, M. Sigward, J. Sohler, J. Speck, R. Strub, T. Todorov, R. Turchetta, P. Hove, D. Vintache, A. Zghiche, M. Ageron, J. Augustin, C. Baty, G. Baulieu, M. Bedjidian, J. Blaha, A. Bonnevaux, G. Boudoul, P. Brunet, E. Chabanat, E. Chabert, R. Chierici, V. Chorowicz, C. Combaret, D. Contardo, R. D. Negra, P. Depasse, O. Drapier, M. Dupanloup, T. Dupasquier, H. Mamouni, N. Estre, J. Fay, S. Gascon, N. Giraud, C. Girerd, G. Guillot, R. Haroutunian, B. Ille, M. Lethuillier, N. Lumb, C. Martin, H. Mathez, G. Maurelli, S. Muanza, P. Pangaud, S. Perriès, O. Ravat, E. Schibler, F. Schirra, G. Smadja, S. Tissot, B. Trocmé, S. Vanzetto, J. Walder, Y. Bagaturia, D. Mjavia, A. Mzhavia, Z. Tsamalaidze, V. Roǐnishvili, R. Adolphi, G. Anagnostou, R. Brauer, W. Braunschweig +499 moresemanticscholar +1 more sourceA novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group.
Cell, 1993 M. MacDonald, C. Ambrose, M. Duyao, R. Myers, Carol S. Lin, L. Srinidhi, G. Barnes, Sherryl A. M. Taylor, M. James, Nicolet Groot, Heather MacFarlane, B. Jenkins, M. Anderson, N. Wexler, J. Gusella, G. Bates, S. Baxendale, H. Hummerich, S. Kirby, M. North, S. Youngman, R. Mott, Günther Zehetner, Z. Sedlacek, A. Poustka, A. Frischauf, H. Lehrach, A. Buckler, D. Church, L. Doucette-Stamm, M. O’Donovan, Laura Riba-Ramírez, Manish S. Shah, V. Stanton, S. Strobel, K. Draths, Jennifer L. Wales, P. Dervan, D. Housman, M. Altherr, R. Shiang, L. Thompson, T. Fielder, J. Wasmuth, D. Tagle, J. Valdes, Lon Elmer, M. Allard, L. Castilla, M. Swaroop, K. Blanchard, F. Collins, R. Snell, T. Holloway, Kathleen Gillespie, N. Datson, D. Shaw, P. Harper +57 moresemanticscholar +1 more sourceTranscriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal +16 morewiley +1 more source
