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Results 111 to 120 of about 6,308,780 (255)

Novell ÑÐµ Ð·Ð´Ñ€ÑƒÐ¶ÑƒÐ²Ð° ÑÐ¾ lntel [PDF]

, 2016
Ð¸Ð·Ð²Ð°Ð ...
Ð¸Ð½Ñ„Ð¾Ñ€Ð¼Ð°Ñ‚Ð¸ÐºÐ°, ÐœÐ•Ð”Ð˜Ð¡ -
core +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source

Adobe Ð³Ð¸ Ð·Ð´Ñ€ÑƒÐ¶ÑƒÐ²Ð° ÑÐ¸Ð»Ð¸Ñ‚Ðµ ÑÐ¾ Netscape [PDF]

, 2016
Ð¸Ð·Ð²Ð°Ð ...
Ð¸Ð½Ñ„Ð¾Ñ€Ð¼Ð°Ñ‚Ð¸ÐºÐ°, ÐœÐ•Ð”Ð˜Ð¡ -
core +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source

ÐŸÐžÐ’ÐÐ–ÐÐ˜Ð¢Ð• ÐÐÐ¡Ð¢ÐÐÐ˜ Ð’Ðž 1995 [PDF]

, 2016
Ð¸Ð·Ð²Ð°Ð ...
Ð¸Ð½Ñ„Ð¾Ñ€Ð¼Ð°Ñ‚Ð¸ÐºÐ°, ÐœÐ•Ð”Ð˜Ð¡ -
core +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source

, 2018
The aim of this study was to evaluate the central obesity, which is a main characteristic of Cushing's syndrome (CS), with dual-energy x-ray absorptiometry (DXA) and to determine DXA indexes that precisely differentiate CS from non CS obese women.
Ð¢Ð¾Ð´Ð¾Ñ€Ð¾Ð²ÑÐºÐ° (Todorovska), Ð›Ð¸Ð´Ð¸Ñ˜Ð° (Lidija) +1 more
core +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source

Ð¢Ñ€Ð¸ ÑÐ»ÑƒÑ‡Ð°Ð¸ Ð½Ð° Syndroma Willi Prader Labhardt Ð²Ð¾ Ð´Ð¾ÐµÐ½ÐµÑ‡ÐºÐ° Ð²Ð¾Ð·Ñ€Ð°ÑÑ‚ [PDF]

, 2017
Authors presented three cases of Willi Prader Labhardt Syndroma whose cardinal symptoms are: psychomotor retardation, proportional obesity, hypogenitalism, a small bifrontal circumference, and carp-like mouth.During the pregnancy, children's mothers felt
Ð¡Ð¿Ð¸Ñ€Ð¾Ð²ÑÐºÐ¸, Ð—Ð¾Ñ€Ð°Ð½ +2 more
core +1 more source

extended supersymmetry
astrophysics
crystal structure

supersymmetric gauge theory
supergravity models