Results 231 to 240 of about 6,154,680 (249)

Rotation reversal of chiral bacterial vortices.

Soft Matter
Htet PH, Lauga E.
europepmc   +1 more source

Dissemination of study results to participants in mental health research: a meta-research review of studies published in high-impact psychiatry journals. [PDF]

BMJ Open
Pierson G, Nassar EL, Adams C, Boruff J, Nordlund J, Hu S, Rice DB, Thombs-Vite M, Co N, Cook V, Thombs BD.   +10 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Association of genetic variation with age at diagnosis in type 1 diabetes. [PDF]

BMJ Open Diabetes Res Care
Vollenbrock CE, Roshandel D, Lee KE, Klein BE, Mul D, van der Klauw MM, Tack CJ, Rewers M, Snell-Bergeon JK, Costacou T, Miller RG, Caramori ML, Mauer M, Aanstoot HJ, Wolffenbuttel BHR, Paterson AD, DCCT/EDIC Research Group, DCCT/EDIC Research Group .   +17 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Cycloruthenated Imines: A Step into the Nanomolar Region. [PDF]

Molecules
Vasil'ev AA, Troshin II, Shangin PG, Voroshilkina KM, Shutkov IA, Nazarov AA, Medved'ko AV.   +6 more
europepmc   +1 more source

Fecal Microbiota Transplantation Donor Screening: Is <i>Dientamoeba fragilis</i> a Valid Criterion for Donor Exclusion? A Longitudinal Study of a Swiss Cohort. [PDF]

Microorganisms
Moser K, Ballif A, Pillonel T, Concu M, Montenegro-Borbolla E, Nickel B, Stampfli C, Ruf MT, Audry M, Kapel N, Gerber S, Jacot D, Bertelli C, Galpérine T.   +13 more
europepmc   +1 more source