Results 91 to 100 of about 96,405 (199)

РазÑабоÑка пÑедложений по ÑовеÑÑенÑÑÐ²Ð¾Ð²Ð°Ð½Ð¸Ñ ÑоÑм кÑедиÑÐ¾Ð²Ð°Ð½Ð¸Ñ ÑÑидиÑеÑÐºÐ¸Ñ Ð»Ð¸Ñ (на пÑимеÑе ÐÐР«СбеÑбанк»)

, 2018
Вели Яралиев
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Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

СиÑÑема пожаÑной Ð¾Ñ ÑÐ°Ð½Ñ Ð¿ÑедпÑиÑÑиÑ

, 2017
Георгий Константинович Яшин
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Tisekta d twuriwin n yismawen imaẓlayen deg yimahilen iseklanen : asaka n tezlatin n Ǧamal Ɛellam

Ussnan
In this article, which explores the use of proper names in Djamel Allam's songs, we will examine this lexical category that lies between two essential domains: linguistics and literature.
Atmane RAHMANI
doaj  

ÐеÑекÑÑÑ ÑÑÑка Ñ Ð½Ð¾Ð²Ð¾Ð½Ð°ÑÐ¾Ð´Ð¶ÐµÐ½Ð¸Ñ Ð´ÑÑей

, 2015
P. S. Rusak
openalex   +2 more sources

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

Molecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf, Daniel Ehinger, Hans Brunnström, Mats Jönsson, Frida Rosengren, Marija Kotevska, Anna Karlsson, Mattias Aine, Christian Frezza, Maria Planck, Elsa Arbajian   +10 more
wiley   +1 more source

ÐлÑнÑко-ÑеÑнологÑÑÐ½Ñ Ð²Ð»Ð°ÑÑивоÑÑÑ Ð¾ÑÐ½Ð¾Ð²Ð½Ð¸Ñ Ð¼Ð°ÑеÑÑалÑв, ÑÐºÑ Ð²Ð¸ÐºÐ¾ÑиÑÑовÑÑÑÑÑÑ Ð² оÑÑопедиÑнÑй ÑÑомаÑологÑÑ

, 2014
Д. Д. Кіндій, В. Д. Кіндій, М. М. Малюченко   +2 more
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Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Ð¢ÐµÑ Ð½Ð¾Ð»Ð¾Ð³Ð¸Ñ Ð¸Ð·Ð³Ð¾ÑÐ¾Ð²Ð»ÐµÐ½Ð¸Ñ Ñзла ÑÑдового Ð¼ÐµÑ Ð°Ð½Ð¸Ð·Ð¼Ð° по наÑÑÑÐ½Ð¾Ð¼Ñ Ð¾Ð±ÑазÑÑ Ð² ÑÑловиÑÑ ÑемонÑа

, 2016
Николай Николаевич Сучков
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