Results 201 to 210 of about 6,151,605 (249)

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, 2013
С. І. Баранник, І. Д. Крижановський, І. Б. Білий, А. С. Бараннік   +3 more
openalex   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Mapping implementation barriers and facilitators of a physical activity consultation in the Portuguese primary healthcare: a qualitative approach combining the Tailored Implementation for Chronic Diseases and Behaviour Change Wheel frameworks. [PDF]

BMJ Open
Silva CS, Silva MN, Encantado J, Franco S, Rosa BA, Mendes R, Teixeira PJ, Godinho CA.   +7 more
europepmc   +1 more source

Зачем программирование грамотному человеку? (Ñ Ñ Ñ Ðµ)

, 2012
Ivan Travkin
openalex   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Impact of Oral Semaglutide on Kidney Outcomes in People With Type 2 Diabetes: Results From the SOUL Randomized Trial. [PDF]

Diabetes Care
Mann JFE, Marx N, Deanfield JE, Emerson SS, Inzucchi SE, McGuire DK, Mulvagh SL, Pop-Busui R, Poulter NR, Engelmann MDM, Hovingh GK, Belmar N, Idorn T, Jeppesen OK, Birkenfeld AL, Amod A, Mankovsky B, Desouza C, Gorgojo-Martinez JJ, Arechavaleta R, Tu ST, Buse JB, SOUL Study Group* .   +22 more
europepmc   +1 more source

СимÑлÑÑанна коÑекÑÑÑ ÑеÑлÑкÑ-езоÑагÑÑÑ Ð¿Ñи ÑÑÑÑÑгÑÑÐ½Ð¾Ð¼Ñ Ð»ÑкÑÐ²Ð°Ð½Ð½Ñ Ð²Ð¸ÑÐ°Ð·ÐºÐ¾Ð²Ð¾Ñ ÑвоÑоби

, 2016
Л. Я. Ковальчук, І. І. Лойко, Р. М. Угляр   +2 more
openalex   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Dissemination of study results to participants in mental health research: a meta-research review of studies published in high-impact psychiatry journals. [PDF]

BMJ Open
Pierson G, Nassar EL, Adams C, Boruff J, Nordlund J, Hu S, Rice DB, Thombs-Vite M, Co N, Cook V, Thombs BD.   +10 more
europepmc   +1 more source

ÐÑенка коммеÑÑеÑкой ÑÑÑекÑивноÑÑи оÑкÑÑÑÐ¸Ñ ÑеÑÑоÑана в ÑÑебно-иÑÑоÑиÑеÑком заповеднике «УÑадÑба Ð.Ð. ÐагаÑина «Холомки»

, 2016
Анастасия Михайловна Шахматова
openalex   +1 more source