Results 21 to 30 of about 6,426,247 (249)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
$$d_{N \Omega }$$ d N Ω production in $$\Omega d$$ Ω d scattering process
In the present work, we propose to investigate the production of $$d_{N \Omega }$$ d N Ω in the $$\Omega ^{-} d \rightarrow p d_{N \Omega }^-$$ Ω - d → p d N Ω - process by utilizing an effective Lagrangian approach, where $$d_{N \Omega }$$ d N Ω is ...
Quan-Yun Guo, Jing Liu, Dian-Yong Chen
doaj +1 more source
Little strings on D n orbifolds
We explore two classes of 6d N = 1 0 $$ \mathcal{N}=\left(1,0\right) $$ little string theories obtained from type IIA/IIB NS5-branes probing D n singularities.
Joonho Kim, Kimyeong Lee
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
4d N $$ \mathcal{N} $$ = 1 from 6d D-type N $$ \mathcal{N} $$ = (1, 0)
Compactifications of 6d N $$ \mathcal{N} $$ = (1, 0) SCFTs give rise to new 4d N $$ \mathcal{N} $$ = 1 SCFTs and shed light on interesting dualities between such theories.
Jin Chen +3 more
doaj +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Названия мать-и-мачехи в удмуртских диалектах [The Names for Coltsfoot (Tussilago farfara L.) Used in Udmurt Dialects]; pp. 53-62 [PDF]
In this article the Udmurt dialect names for coltsfoot (Tussilago farfara L.) are discussed, their word-formation structure is analyzed, the etymology of their components is given and the basic naming principles are defined.
Marianna Rifovna Nasibullina
doaj +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source

