Results 161 to 170 of about 6,270,495 (248)
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
D. Seifried, N. Stark: Energiedienstleistungen - Rezension
Technikfolgenabschätzung – Theorie und Praxis, 1994 Torsten Fleischer
doaj +1 more source
Optimization of systemic AAV9 gene therapy in Niemann-Pick disease, type C1 mice. [PDF]
Life Sci AllianceMylvara AV +11 more
europepmc +1 more source
4. BIOS - ПриÑтап до тврдиот диÑк
, 2016 изваР...
информатика, МЕДИС -
core
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
D. N. Wadia: a Biographical Sketch
Journal of the Palaeontological Society of India, 1957 doaj +1 more source
New deep-sea Amphipoda from the Clarion-Clipperton Zone: 24 new species described under the Sustainable Seabed Knowledge Initiative: One Thousand Reasons campaign. [PDF]
ZookeysJażdżewska AM, Horton T.
europepmc +1 more source