A critical analysis of the IMWG multiple myeloma complete response criterion in the era of mass spectrometry. [PDF]
HemaSphere, Volume 10, Issue 2, February 2026.
Puig N +24 more
europepmc +2 more sources
European Myeloma Network Group Consensus Statement on the use of next-generation sequencing for prognostic stratification of newly diagnosed multiple myeloma. [PDF]
Abstract Given the evolving understanding of genetic risk factors in multiple myeloma (MM), this paper assesses whether next‐generation sequencing (NGS) could complement or even replace fluorescence in situ hybridization (FISH) at diagnosis. A structured consensus process within European Myeloma Network (EMN) clinical and laboratory groups was ...
Bolli N +31 more
europepmc +2 more sources
European Expert Panel Consensus on Outpatient Administration of Teclistamab and Talquetamab in Patients With Multiple Myeloma: Feasibility, Key Considerations, and Future Directions. [PDF]
ABSTRACT Objectives Teclistamab and talquetamab treatments are typically initiated in a hospital due to the potential risk of cytokine release syndrome. However, emerging data support the potential for outpatient administration (i.e., administration without overnight hospital admission).
Lund T +12 more
europepmc +2 more sources
High-risk features of early relapse in newly-diagnosed multiple myeloma: The impact of cytogenetics and response to initial therapy. [PDF]
Abstract Patients with newly‐diagnosed multiple myeloma (MM) who experience early relapse (ER) have dismal overall survival (OS). Their prospective identification, either before or soon after treatment initiation, is paramount to use alternative approaches and prevent ER.
Manubens A +33 more
europepmc +2 more sources
30-Minute infusion of isatuximab in patients with newly diagnosed multiple myeloma: Results of a Phase 1b study analysis. [PDF]
HemaSphere, Volume 8, Issue 11, November 2024.
Ocio EM +12 more
europepmc +2 more sources
High-risk cytogenetic abnormalities in multiple myeloma: PETHEMA-GEM experience. [PDF]
Abstract This study examines the impact of cytogenetic abnormalities and their co‐segregation on the prognosis of newly diagnosed multiple myeloma patients. The analysis included 1304 patients from four different GEM‐PETHEMA clinical trials. Genetic alterations, such as t(4;14), t(14;16), del(17p), +1q, and del(1p), were investigated using FISH on CD38
González-Calle V +23 more
europepmc +2 more sources
Estudaram-se os efeitos da substituição na dieta da silagem de milho por silagem de girassol (0, 33 e 66% MS) no comportamento ingestivo de novilhos em confinamento. Utilizaram-se nove novilhos castrados com peso vivo e idade média inicial de 288 kg e 20
Leandro da Silva Freitas +5 more
doaj +1 more source
O objetivo deste trabalho foi estudar o efeito da substituição do milho por palma forrageira sobre o comportamento ingestivo de 8 vacas 5/8 Holandês-Zebu, distribuídas em 2 quadrados latinos 4 x 4.
Rosângela Maria Brito de Lima +9 more
doaj +1 more source
Este estudo foi conduzido com o objetivo de avaliar a influência da frequência no fornecimento de volumoso e concentrado e/ou da categoria animal sobre o comportamento ingestivo de bovinos.
Raul Dirceu Pazdiora +5 more
doaj +1 more source
O presente trabalho teve por objetivo avaliar o consumo e comportamento ingestivo de caprinos e ovinos alimentados com palma Gigante (Opuntia fícus-indica Mill) e palma Orelha-de-elefante (Opuntia sp.).
Maria Caroline de Almeida Cavalcanti +5 more
doaj +1 more source

