Results 21 to 30 of about 3,192 (113)

Understanding and addressing resistance to IMiDs immunomodulatory compounds in multiple myeloma

The FEBS Journal, EarlyView.
IMiDs are pivotal in the treatment of multiple myeloma. Mechanisms of resistance comprise cell intrinsic and extrinsic pathways, involving tumour microenvironment, immune cell dysfunction, CRBN‐dependent and independent genetic drivers and epigenetic changes.
Maria‐Cynthia Fuentes‐Lacouture, Devi Nandana, Karthik Ramasamy, Anjan Thakurta   +3 more
wiley   +1 more source

The Changing Landscape of Maintenance Therapy in Newly Diagnosed Multiple Myeloma: A Systematic Review With Network Meta‐Analysis of the European Myeloma Network (EMN)

American Journal of Hematology, Volume 101, Issue 9, Page 2353-2370, September 2026.
Our meta‐analysis showed significant improvement of PFS with lenalidomide, proteasome inhibitors, and CD38‐based therapies. A significant OS benefit was noted only with lenalidomide in transplant‐eligible (TE) patients, while CD38‐directed therapy showed a trend toward improved OS.
Heinz Ludwig, Evangelos Terpos, Francesca Gay, Niels W. C. J. van de Donk, Sarah Bernhard, Monika Engelhardt, Gordon Cook, Fredrik Schjesvold, Hermann Einsele, Graham Jackson, Charlotte Pawlyn, María‐Victoria Mateos, Sonja Zweegman, Martin Schreder, Meral Beksaç, Christoph Driessen, Enrique M. Ocio, Rakesh Popat, Leo Rasche, Cyrille Touzeau, Pellegrino Musto, Annemiek Broijl, Meletios Dimopoulos, Roman Hajek, Mario Boccadoro, Pieter Sonneveld   +25 more
wiley   +1 more source

Comportamento ingestivo de ovinos Santa Inês alimentados com dietas contendo farelo de cacau Ingestive behavior of Santa Inês sheep fed diets with cocoa meal

Revista Brasileira de Zootecnia, 2008
O experimento foi conduzido para avaliar o comportamento ingestivo de ovinos alimentados com dietas contendo farelo de cacau. Foram utilizados 16 ovinos Santa Inês fêmeas, não-gestantes e não-lactantes, com peso corporal médio de 25 kg e aproximadamente ...
Gleidson Giordano Pinto de Carvalho, Aureliano José Vieira Pires, Robério Rodrigues Silva, Leandro Sampaio Oliveira Ribeiro, Daiane Maria Trindade Chagas   +4 more
doaj   +1 more source

SmartTur+ECO: A Multimodal Conversational Recommender System Integrating Virtual Reality and Gamification for Smart Tourism

Expert Systems, Volume 43, Issue 9, September 2026.
ABSTRACT This paper presents SmartTur+ECO, a system for tourist attractions that integrates conversational recommendation systems (CRS), virtual reality (VR) and gamification. It efficiently gathers trip data and elicits user preferences through interactions with a chatbot, addressing the user‐cold start problem common in tourism.
Juan Carlos Carrillo, Victoria Beltran, Laura Sebastia, Eva Onaindia, Ignacio Seguí, Alfonso Lopez, Jose Carlos Sola   +6 more
wiley   +1 more source

Comportamento ingestivo de cabras Alpinas em lactação alimentadas com dietas contendo diferentes níveis de fibra em detergente neutro proveniente da forragem Feeding behavior of lactating Alpine goats fed diets containing different dietary levels of forage neutral detergent fiber

Revista Brasileira de Zootecnia, 2006
Avaliou-se o efeito de diferentes níveis de fibra em detergente neutro proveniente da forragem (FDNF) na dieta sobre o comportamento ingestivo de cabras em lactação.
Sérgio Carvalho, Marcelo Teixeira Rodrigues, Renata Helena Branco, Carla Aparecida Florentino Rodrigues   +3 more
doaj   +1 more source

THE CONTESTED CITY OF VENICE: Caring for Commodified Common Infrastructures in a Touristified Environment

International Journal of Urban and Regional Research, Volume 50, Issue 4, Page 1053-1064, July 2026.
Abstract In this essay I reveal contested common infrastructures in the interplay between vanishing public infrastructures in Venice and lack of care by governmental actors in a city with a shrinking number of inhabitants. I examine care and commodified public infrastructures in heritage cities facing mass tourism and climate change effects by zooming ...
Cornelia Dlabaja
wiley   +1 more source

Ingestive behavior of Nellore cows and their straightbred or crossbred calves Comportamento em pastejo de vacas Nelores amamentando bezerros Nelores ou mestiços Simental × Nelore

Revista Brasileira de Zootecnia, 2010
This trial aimed to investigate the influence of calf genetic group on the ingestive behavior of Nellore dams and their offspring on pasture. Twenty one primiparous and multiparous Nellore cows were assigned to the experiment; 13 cows nursed straightbred
Fernando Miranda de Vargas Junior, Francisco Stefano Wechsler, Patrícia Rossi, Marcus Vinicius Morais de Oliveira, Patrick Schmidt   +4 more
doaj   +1 more source

Comportamento ingestivo em caprinos alimentados com dietas contendo cana-de-açúcar tratada com óxido de cálcio Ingestive behavior in goats fed diets containing sugar cane treated with calcium oxide

Revista Brasileira de Zootecnia, 2011
Objetivou-se avaliar o efeito do tratamento da cana-de-açúcar com óxido de cálcio (CaO) sobre o comportamento ingestivo em caprinos. Foram utilizados oito caprinos da raça Saanen, machos castrados, com peso corporal médio de 22,6 kg e 4 meses de idade ...
Gleidson Giordano Pinto de Carvalho, Rasmo Garcia, Aureliano José Vieira Pires, Edenio Detmann, Leandro Sampaio Oliveira Ribeiro, Daiane Maria Trindade Chagas, Robério Rodrigues Silva, Bianca Damasceno Pinho   +7 more
doaj   +1 more source

Elimination of acrolein from cider by addition of sulphur dioxide

Journal of Chemical Technology &Biotechnology, Volume 101, Issue 6, Page 1254-1262, June 2026.
Abstract BACKGROUND Acrolein is a toxic substance that sometimes appears in ciders, imparting an unpleasant taste and odour, which spoils the beverage entirely. Based on the reaction between acrolein and sulphur dioxide to form adducts, some oenologists of the Basque Country and Navarre (Northern Spain) use sulphur dioxide to remove acrolein.
Enaitz de las Heras, Andoni Zuriarrain‐Ocio, Juan Zuriarrain, Oier Etxebeste, Iñaki Berregi   +4 more
wiley   +1 more source

Online Risk Behaviours Among Adolescents: Identifying Areas of Digital Vulnerability

Children &Society, Volume 40, Issue 3, Page 474-488, May 2026.
ABSTRACT As a period during which they undergo important physical, emotional and social changes, adolescence is of great importance for minors. In addition, adolescence is an initial stage in terms of children's use of their own mobile devices and their first access to the internet and social networks, an activity that becomes a generalised habit in ...
Sonia Carcelén‐García, Oliver Carrero Márquez, Myriam Durán Vilches   +2 more
wiley   +1 more source