Results 31 to 40 of about 114,466 (193)

A Comparative Study of the Structural Dynamics of Four Terminal Uridylyl Transferases. [PDF]

, 2017
African trypanosomiasis occurs in 36 countries in sub-Saharan Africa with 10,000 reported cases annually. No definitive remedy is currently available and if left untreated, the disease becomes fatal.
Amaro, Rommie E, Cheng, Kevin J, Demir, Özlem   +2 more
core   +1 more source

Biodegradable Carbonate Nanogels Loaded with Anti MFAP‐5 siRNA for Anti‐stromal Therapy of Hepatocellular Carcinoma

Advanced Science, EarlyView.
Polycarbonate nanogels enable lipid‐free delivery of anti‐MFAP‐5 siRNA into cancer‐associated fibroblasts (CAF) in hepatocellular carcinoma. In a cirrhotic murine model, this approach silences MFAP‐5, reduces fibroblast activation, and suppresses tumor growth by inhibiting NOTCH/Hes1‐driven angiogenesis. CAF‐targeted MFAP‐5 RNAi and conserved signaling
Paul Schneider, Alexander Fuchs, Michael Fichter, Vanessa Bolduan, Jenny Schunke, Özlem Akilli, Nádia C. Correia, Yannick Ehlers, Christian Czysch, Pia Winterwerber, Eliana Stanganello, Barbara Schrörs, Mustafa Diken, Christoph Eckert, Shusruto Rishik, Andreas Keller, Jörn M. Schattenberg, Stephan Grabbe, Matthias Bros, Lutz Nuhn, Leonard Kaps   +20 more
wiley   +1 more source

Effect of varying magnetic fields on targeted gene delivery of nucleic acid-based molecules [PDF]

, 2014
This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014), Gözüaçik, D, Koşar, A, Oral, Ö, Yaǧci Acar, HF, Çikim, T, Ünal, Ö   +6 more
core  

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

A parametric evaluation of the removal as(III) and as(V) from aqueous water by red mud [PDF]

, 2010
In the present study, removal of arsenide (As(III)) and arsenate As(V) ions from water/wastewater by adsorption on red mud is investigated. Laboratory experiments were carried out to analyze removal capacity of the adsorbents, to achieve adsorption ...
Kocabaş, Özlem Züleyha, Yürüm, Yuda
core  

Researcher–Entrepreneur Relationship and Performance of Innovative Startups

International Journal of Finance &Economics, EarlyView.
ABSTRACT Many innovative startups are joint ventures between researchers and entrepreneurs, who collaborate in R&D and product commercialization. Government policies such as grants, subsidies, and patent licensing fees act as Pigouvian subsidies, incentivizing R&D by bridging the gap between the social and private returns of innovation.
Yangguang Huang, Helen Hui
wiley   +1 more source

Morphology-Syntax interface for Turkish LFG [PDF]

, 2006
This paper investigates the use of sublexical units as a solution to handling the complex morphology with productive derivational processes, in the development of a lexical functional grammar for Turkish.
Cetinoglu, Ozlem, Oflazer, Kemal, Çetinoğlu, Özlem   +2 more
core   +1 more source

Cellular Responses to Tartrazine and Sulfanilic Acid Exposure in BEAS‐2B Cells: Viability, Apoptosis, and DNA Damage

Journal of Applied Toxicology, EarlyView.
ABSTRACT Tartrazine is a synthetic azo dye widely used in food, pharmaceutical, and cosmetic products, resulting in extensive human exposure, while its toxicity and that of its primary metabolite, sulfanilic acid, remain controversial. Considering the reported association of tartrazine with hypersensitivity and allergic‐like reactions, human bronchial ...
Merve Baysal, Abdullah Burak Karaduman, Büşra Korkut Çelikateş, Merve Güven, Özlem Atlı‐Eklioğlu, Sinem Ilgın   +5 more
wiley   +1 more source

Geçmişle Aktif Etkileşim Aracı olarak Sosyal Medya: Facebook “Yeniden Yenidoğanlılar” Örneği

Yeni Medya
En genel tanımlamayla geçmişe duyulan özlem anlamına gelen nostalji kavramı, zamanla doğrudan ilişkiliyken genellikle göz ardı edilen nokta zamanın mekâna olan bağlılığı ve özlemin kollektif bir duygu olabileceğidir.
Meltem Yılmaz Bilecen
doaj   +1 more source

KIRIK BİR KALP HİKÂYESİ: OSMAN FAHRİ ŞİİRİNDE KAYIP NESNE

Akademik İncelemeler Dergisi, 2018
Sanat eserleri yaratıcılarının bilinçdışlarından izler taşımaktadır. Hiçbir sanat eseri onu yaratanın bilinçdışından soyutlanmış bir şekilde olarak ortaya çıkamaz. Henüz 30 yaşında iken kendi hayatına son veren Osman Fahri’nin; 1909-1920 yılları arasında
Zihniye Okray
doaj   +1 more source