Results 71 to 80 of about 4,388,618 (289)

Linguistic 'mudes' and the de-ethnicization of language choice in Catalonia [PDF]

open access: yes, 2012
Catalan speakers have traditionally constructed the Catalan language as the main emblem of their identity even as migration filled the country with substantial numbers of speakers of Castilian. Although Catalan speakers have been bilingual in Catalan and
González Balletbó, Isaac   +1 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

20 anys, nova etapa per a "Llengua i Ús" [PDF]

open access: yes, 2013
L'editorial presenta els continguts d'aquest número 53, en què la revista 'Llengua i Ús' estrena un nou ...
Franquesa, Ester
core  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Integrated series transformer in cascade converters for photovoltaic energy systems [PDF]

open access: yes, 2018
This paper proposes a novel configuration for photovoltaic applications based on a cascade converter topology. The series connection between modules is achieved through the magnetic core of the integrated series transformer, therefore an inherent ...
Atef Abbas Elsaharty, Mohamed   +2 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

PARTICULAR ASPECTS OF THE WTO MECHANISMS APPLICATION TO PROTECT THE NATIONAL ECONOMIC INTERESTS OF UKRAINE

open access: yesBaltic Journal of Economic Studies, 2016
The purpose of the paper is to analyze the issue of applying by Ukraine of mechanisms developed in the legal framework by the World Trade Organization to protect the internal market in order to prepare appropriate recommendations to state power ...
Ivan Us
doaj  

Effects of oil spillage on Soil and Surface Water in Odoro Ikot Ukanafun Area Akwa Ibom State

open access: yesJournal of Applied Sciences and Environmental Management, 2013
A hydrogeochemical survey of water and soil sample in Odoro Ikot and its environment was carried out using Atomic Absorption Spectrometry (AAS) techniques. It was done to assess the impact of oil spillage on soil and surface water in the area.
US Ido, N Egesi
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

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