Results 61 to 70 of about 288,536 (293)

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

British Journal of Clinical Pharmacology, EarlyView.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić, Patrick Eustaquio, Elvira Meni Maria Gkrinia, Ivana Stević, Eugen Javor, Yun Wah Lam, Slobodan Janković, Dinko Vitezić   +7 more
wiley   +1 more source

Leucemia mieloide extramedular con compromiso endometrial: reporte de un caso y revisión de la literatura Extramedullary myelogenous leukemia with endometrial involvement: a case report and literature review

Revista Colombiana de Obstetricia y Ginecología, 2007
La leucemia mieloide extramedular (LME), también conocida como sarcoma granulocítico, es una manifestación extramedular de la leucemia mieloide aguda. Puede presentarse virtualmente en todos los sitios del organismo y en cualquier momento de la evolución
Germán García-Soto, Juan de Jesús Pachón-Rincón, Jorge A Castaño, José Domingo Torres, Elvia Inés Gómez   +4 more
doaj  

Útero, psiquis y climaterio: un acercamiento desde la endocrinología antropológica [PDF]

, 2015
The female gonadal cycle has been ancestrally linked to traits of an emotional and mutable mood, partly attributed to moon phases. This would pave the way along centuries to consider menstruation as something impure and, in the western civilization, even
M. Melián, Elvira
core   +2 more sources

In utero and peripubertal metals exposure in relation to reproductive hormones and sexual maturation and progression among girls in Mexico City.

Environmental Research, 2019
There is increasing evidence that several metals are endocrine disrupting chemicals (EDCs). In utero development and adolescence are critical windows of susceptibility to EDC exposure.
Pahriya Ashrap, B. Sánchez, M. Téllez-Rojo, N. Basu, M. Tamayo-Ortiz, K. Peterson, J. Meeker, Deborah J. Watkins   +7 more
semanticscholar   +1 more source

Use of antiemetics in early pregnancy 2012–2022: A cross‐sectional study

British Journal of Clinical Pharmacology, EarlyView.
Aim Nausea and vomiting in pregnancy impact quality of life, yet many pregnant women feel dismissed by healthcare professionals, despite the safety of first‐line antiemetic treatments for both mother and fetus. Therefore, this study aims to describe the prevalence of patient‐reported antiemetic use in early pregnancy in Copenhagen, Denmark, the changes
Katrine Bak Wraae, Nanna Roed Ballegaard, Mie Lærkeholm Hede, Line Buchgreitz, Ane Lilleøre Rom, Hanne Kristine Hegaard, Nina Olsén Nathan   +6 more
wiley   +1 more source

Leiomioma uterino en paciente con síndrome de Mayer-Rokitansky-Küster-Hauser: reporte de caso

Revista Colombiana de Obstetricia y Ginecología, 2010
Objetivo: el síndrome de Mayer-Rokitansky-Küster-Hauser (MRKH) es una malformación congénita del útero y la parte superior de la vagina en las mujeres que muestran características sexuales secundarias normales y cariotipo 46 XX.
Mario Arturo González-Mariño, Mario Pérez-Solano   +1 more
doaj  

Vascularização uterina de éguas prenhes de jumento e de garanhão monitoradas por ultrassonografia Doppler

Pesquisa Veterinária Brasileira
RESUMO: Este estudo teve como objetivo analisar e descrever os achados ultrassonográficos do útero de éguas gestantes de diferentes idades, de jumento e garanhão, utilizando a técnica de ultrassonografia Doppler Espectral, visando caracterizar os índices
Sabina G.C. Lemos, Diego G. Campos, Camila S.C. Ferreira, Mário F.A. Balaro, Luís E.R. Cunha, Aline E. Pinna, Felipe Z. Brandão   +6 more
doaj   +1 more source

Cancro do colo do útero: que rastreio? [PDF]

, 2008
O cancro do colo do útero é um dos cancros evitáveis mais frequente nas mulheres, Ferlay (2004) e Parkin(2005). O padrão epidemiológico da doença, caracterizado por um período longo entre a detecção das primeiras lesões e a instalação da doença ...
Pereira, Andreia, Rocha, Ana Maria A. C., Tavares, Fernando   +2 more
core  

Neurodevelopmental delay in normocephalic children with in utero exposure to Zika virus

BMJ Paediatrics Open, 2019
Neurodevelopment in 29 normocephalic children with in utero exposure to Zika virus (ZIKV) was evaluated by the Bayley Scales of Infant and Toddler Development-Third Edition. Ten (35%) infants presented neurodevelopment delay.
A. Faiçal, J. C. de Oliveira, J. Oliveira, Breno L. S. de Almeida, Iluska Andrade Agra, L. Alcântara, A. Acosta, I. D. de Siqueira   +7 more
semanticscholar   +1 more source

Identification of major congenital malformations based on healthcare databases in France: A proof‐of‐concept study using the epi‐meres nationwide mother–child register

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Besides registries, healthcare databases can provide useful information for assessing the frequency of major congenital malformations (MCMs) and investigating their risk factors, particularly medication exposures. This study aimed to assess the validity of MCMs identification based on French national, comprehensive healthcare databases ...
Tom Duchemin, Lise Marty, Jérôme Drouin, Sara Miranda, Jérémie Botton, Valérie Olié, Alain Weill, Rosemary Dray‐Spira   +7 more
wiley   +1 more source