Results 81 to 90 of about 288,536 (293)

A White Paper on Advancing Long‐Acting Therapeutics for Maternal and Pediatric Health by Bridging Gaps in Clinical Research, Access and Regulation

Clinical Pharmacology &Therapeutics, EarlyView.
As use cases for long‐acting therapeutics expand across clinical indications, there is a critical need to ensure the inclusion of women who are pregnant or breastfeeding, infants and children—populations with a historical gap in the availability of interventions already approved for use in adults.
Moherndran Archary, Robert Bies, Osei Boateng, Rachel Daley, Pierre Gashema, Mili Karina, Emily Njuguna, Sharon Nachman, Nathaniel Nkrumah, Carolyne Odula, Andrew Owen, Ethel D. Weld, Prajith Venkatasubramanian, Adeniyi Olagunju, on behalf of the Community of Practice for Long‐acting Therapeutics for Maternal and Paediatric Health, Rana Abutaima, Dorothy Akongo, Abdulnaser Alsharaa, Moherndran Archary, Shakir Atoyebi, Benoit Bestgen, Robert Bies, Osei Boateng, Andrew Butler, Edmund Capparelli, Rachel Daley, Layla Davies, Joelle Dountio, Henry Enzama, Pierre Gashema, Katila George, Dan Hawcutt, Rene Holm, Patrick Gad Iradukunda, Elodie Jambert, Mili Karina, Linda Lewis, Grace Miheso, Sebastien Morin, Andrew Morrison, Sharon Nachman, Shadia Nakalema, Emily Njunga, Nathaniel Nkrumah, Carolyne Odula‐Obonyo, Brenda Okware, Adeniyi Olagunju, Andrew Owen, Martina Penazzato, Natella Rakhmanina, Mphako Brighton Ratlabyana, Rachel Scott, Kimberly Struble, Andre‐Marie Tchouatieu, Catherine Unsworth, Prajith Venkatasubramanian, Catriona Waitt, Ethel Weld, Janine Winterbottom, Leena Zino   +59 more
wiley   +1 more source

Assessment of satisfaction in patients after hysterectomy by myomatous uterus [PDF]

, 2012
Objetivo: el objetivo de este estudio es evaluar los resultados, en cuanto a calidad de vida, de aquellas pacientes que han sido sometidas a una histerectomía por útero miomatoso.
Abehsera, D., De Santiago García, Francisco Javier, Hernández Gutiérrez, A., Panal, M.   +3 more
core   +1 more source

Embryonic cerebrospinal fluid pressure in fetal mice in utero: External factors pressurize the intraventricular space

Developmental Dynamics, EarlyView.
Abstract Background Previous experiments inducing leakage of embryonic cerebrospinal fluid (CSF) suggest the necessity of intraventricular CSF pressure (PCSF) for brain morphogenesis. Nevertheless, how embryonic PCSF occurs is unclear, especially in utero. Results Using a Landis water manometer, we measured PCSF in fetal mice isolated from the amniotic
Koichiro Tsujikawa, Reina Muramatsu, Takaki Miyata   +2 more
wiley   +1 more source

Miomatosis uterina, sintomatología urinaria y alteraciones sexuales en mujeres con indicación de tratamiento quirúrgico [PDF]

, 2016
Introducción Las pacientes con miomas uterinos pueden llegar a sufrir de síntomas urinarios y de disfunción sexual. Es para nosotros importante conocer la frecuencia de estas patologías en pacientes con miomas con indicación de cirugía atendidos en el ...
Garcia Rueda, Sandy Julieth, Russi Russi, Viviana Ariela   +1 more
core   +1 more source

In Utero Heat Stress Alters the Offspring Epigenome

Scientific Reports, 2018
Exposure to intrauterine heat stress during late gestation affects offspring performance into adulthood. However, underlying mechanistic links between thermal insult in fetal life and postnatal outcomes are not completely understood.
A. Skibiel, Francisco Peñagaricano, R. Amorín, B. Ahmed, G. Dahl, J. Laporta   +5 more
semanticscholar   +1 more source

The β integrin modulates serotonin sensitivity via NPxY motifs to regulate egg laying and mechanosensation behaviors in Caenorhabditis elegans

Developmental Dynamics, EarlyView.
Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm, Daniel Dogeon Lee, Zhongqiang Qiu, Angela Haeun Choi, Meghana Kolluri, Michael J. Olsen, Lianzijun Wang, Myeongwoo Lee   +7 more
wiley   +1 more source

Fístula útero consecutiva a una cesárea abdominal

Cirugía del Uruguay, 2019
Presentado en la sesión del 17 de julio de ...
D. Prat
doaj  

“HALLAZGOS RADIOLOGICOS EN LA HISTEROSALPINGOGRAFÍA EN PACIENTES CON DIAGNOSTICO DE INFERTILIDAD EN EL CENTRO MEDICO ISSEMYM ECETEPEC” [PDF]

, 2013
La infertilidad se define como la incapacidad de concebir un producto después de 12 meses de coito sin uso de algún método de planificación familiar.
García Morales, Tania Edith, Vargas Mejía, Juan Ángel   +1 more
core  

Selection in utero and population health: Theory and typology of research

SSM - population health, 2018
Public health researchers may assume, based on the fetal origins literature, that “scarring” of birth cohorts describes the population response to modern-day stressors.
T. Bruckner, R. Catalano
semanticscholar   +1 more source

Bridging maternal effects and epitranscriptomics: A novel perspective in developmental biology

Developmental Dynamics, EarlyView.
Abstract Maternal effects, encompassing both genetic (maternally expressed gene products) and non‐genetic (maternal state) influences, are powerful determinants of offspring phenotype, yet their RNA‐level mechanisms remain incompletely resolved. In parallel, epitranscriptomics, an emerging field centered on chemical modifications to RNA, has revealed ...
Ehsan Pashay Ahi
wiley   +1 more source