Results 151 to 160 of about 1,298,122 (296)

High-Level Object Oriented Genetic Programming in Logistic Warehouse Optimization [PDF]

open access: yes, 2014
Disertační práce je zaměřena na optimalizaci průběhu pracovních operací v logistických skladech a distribučních centrech. Hlavním cílem je optimalizovat procesy plánování, rozvrhování a odbavování.
Karásek, Jan
core  

Centaurealovricii, a new species of C. sect. Centaurea (Asteraceae) from Croatia. [PDF]

open access: yesPhytoKeys, 2022
Bogdanović S   +4 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Algorithm for Virtual Waiting Room Handling [PDF]

open access: yes, 2016
Tato práce se věnuje problematice virtuálních čekáren, informuje o aktuálně dostupných produktech a programovacích prostředcích, hodnotí je a nabízí řešení nedostatků zjištěných v současném stavu.
Mrázek, Patrik
core  

An updated evolutionary classification of CRISPR–Cas systems

open access: yesNature Reviews Microbiology, 2015
K. Makarova   +20 more
semanticscholar   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Static analysis of residential building [PDF]

open access: yes, 2014
Tématem diplomové práce je statická analýza bytového domu. Práce se zabývá posouzením původního řešení a navrhnutím varianty nové. Zaměřuje se na statické řešení monolitické železobetonové žebrové desky a věnuje se posouzení této žebrové desky podle ...
Hanzlík, Petr
core  

The next generation of CRISPR–Cas technologies and applications

open access: yesNature reviews. Molecular cell biology, 2019
Adrian Pickar-Oliver, C. Gersbach
semanticscholar   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Raba avgmentiranih preteklih glagolskih časov v stari indijščini

open access: yesSlavistična Revija, 2007
Članek skuša z enega zornega kota osvetliti slabo raziskano problematiko sintakse staroindijskega glagola. Avtorica prikaže različne načine rabe vedskih in klasičnih avgmentiranih glagolskih časov in analizira funkcionalno razliko med njimi, natančneje ...
Nataša TERBOVŠEK COKLIN
doaj  

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