Results 171 to 180 of about 1,298,122 (296)
Znanost, zgodovina, napredek: mit kot zgodba o času, ujeta med večnost in neskončnost
Miha Pintarič
doaj +1 more source
Táto štúdia pojednáva o možnostiach využitia vizuálnych systémoch v dopravných technológiách. Rozoberá možnosti vizuálneho systému ako systému pre zvýšenie vonkajšej bezpečnosti tak aj systému pre počítačové pozorovanie a pre monitorovanie ostražitosti ...
Rudolf Volner
doaj
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
»Zgodovina ne teče naravnost, cikcakasto gre«: percepcija časa v Magrisovem romanu Na slepo
Irena Prosenc Šegula
doaj +1 more source
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
CRISPR-Cas systems for editing, regulating and targeting genomes
Jeffry D. Sander, J. Joung
semanticscholar +1 more source
The effects of grammatical gender on the processing of occupational role names in Slovene: An event-related potential study. [PDF]
Mikić Ljubi J +3 more
europepmc +1 more source
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source

