Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Populismus in Europa: Von den Rändern zum Mainstream
Totalitarismus und Demokratie, 2020 Despite the enormous growth of academic interest during the past years, there is still significantly more known about the consequences than the causes of populism. This issue can be addressed by analyzing not only
Cas Mudde
doaj +1 more source
Preservation of forest soil and vegetation in the Capercaillie (Tetrao urogallus L.) habitat within the eastern Karavanke region an the eastern Kamnik-Savinja Alps in Slovenia [PDF]
, 2017 V študiji smo preuevali talne in vegetacijske razmere na devetih reprezentativnih ploskvah v habitatu divjega petelina (Tetrao urogallus L.) v visokogorju vzhodnih Karavank in vzhodnih Kamniško-Savinjskih Alp. Raziskave so potekale na ploskvah v razlinih
Kutnar, Lado +2 more
core
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
ÚLOHA MULTILATERACE PŘI ZVYŠOVANÍ BEZPEČNOSTI LETECKÉ DOPRAVY
Perner’s Contacts, 2011 Článek popisuje využití multilateračních systémů pro zvýšení bezpečnosti a kapacity v letecké dopravy. Práce zahrnuje popis principu činnosti multilateračních systémů v závislosti na časových architekturách. Závěr práce je věnován WAM systémům.
Marcela Ujcová
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Zao čas u verovanju slovenskih naroda
«Neroven», «lih čas» v pover'jah slavjanskih narodov
Studia Mythologica Slavica, 2011 According to the Slavic beliefs, during the circulation of the time, at the shift between the night and the day, there is a dangerous interlude, when the man is exposed to the possibility of misfortunate accident or even death.
Ljubinko Radenković
doaj +1 more source
IAVCEI: from small beginnings to a vibrant international association [PDF]
History of Geo- and Space Sciences, 2019 The International Association for Volcanology and Chemistry of the Earth's Interior (IAVCEI) was formed following the end of World War I at the inaugural general assembly (GA) of the International Research Council in Brussels in 1919, where the ...
R. A. F. Cas, R. A. F. Cas
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
KONKURENCIESCHOPNOSŤ HROMADNEJ OSOBNEJ DOPRAVY
Perner’s Contacts, 2007 Príspevok rozoberá problematiku vývoja prepravných výkonov v hromadnej osobnej doprave. Analyzuje mestskú hromadnú dopravu, regionálnu dopravu a diaľkovú dopravu.
Miloš Poliak
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