Results 21 to 30 of about 1,298,122 (296)
Bacteriophages suppress CRISPR–Cas immunity using RNA-based anti-CRISPRs
Nature, 2023 Many bacteria use CRISPR–Cas systems to combat mobile genetic elements, such as bacteriophages and plasmids^ 1 . In turn, these invasive elements have evolved anti-CRISPR proteins to block host immunity^ 2 , 3 .
S. Camara-Wilpert +7 more
semanticscholar +1 more source
CRISPR-Cas guides the future of genetic engineering
Science, 2018 The diversity, modularity, and efficacy of CRISPR-Cas systems are driving a biotechnological revolution. RNA-guided Cas enzymes have been adopted as tools to manipulate the genomes of cultured cells, animals, and plants, accelerating the pace of ...
G. Knott, J. Doudna
semanticscholar +1 more source
Mesto ponoči (na primeru Maribora)
Dela, 2016 Prispevek obravnava mesto v nočnem času. Posebnost obravnavane tematike je časovna razsežnost prostora ter območja – kraji, ki »živijo« ponoči. Noč ima ekonomsko, kulturno, oblikovno in socialno vsebino in prav te lastnosti določajo spoznavanje mesta v ...
Vladimir Drozg
doaj +1 more source
A CRISPR-Cas autocatalysis-driven feedback amplification network for supersensitive DNA diagnostics
Science Advances, 2021 A CRISPR-Cas–driven positive feedback circuit with exponential dynamic enables ultrasensitive detection of genomic DNA. Artificial nucleic acid circuits with precisely controllable dynamic and function have shown great promise in biosensing, but their ...
K. Shi +8 more
semanticscholar +1 more source
Peter Green: Katul in njegov čas
Clotho, 2023 O Katulu vemo zelo malo zanesljivega in celo večino tega je treba razbrati iz njegovega lastnega literarnega dela. To je vedno tvegan pristop, ki mu kritika danes večinoma nasprotuje (četudi je kritika vedno spremenljiva in znaki teh sprememb so že v ...
Peter Green +7 more
doaj +1 more source
International Journal of Molecular Sciences, 2021 According to Darwin’s theory, endless evolution leads to a revolution. One such example is the Clustered Regularly Interspaced Palindromic Repeats (CRISPR)–Cas system, an adaptive immunity system in most archaea and many bacteria. Gene editing technology
Sweta Nidhi +7 more
semanticscholar +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Državljansko samovarovanje [PDF]
, 2012 Predstaviti državljansko samovarovanje, ki je v Republiki Sloveniji zaenkrat še daleč do uresničitve in umestitve v naš varnostni sistem oziroma nacionalno varnostni sistem Republike Slovenije.
Frlež, Darja, Čas, Tomaž
core
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Kvalitativní čas v Proustově Hledání ztraceného času // The qualitative conception of time in Proust’s In Search of Lost Time [PDF]
Svět Literatury, 2015 This paper aims to display the most significant feature of Proust’s thinking of time consisting in a specific connection between the time as a concrete lived quality and the extra-temporal qualitative difference or essence.
Alena Tesková
doaj