Results 21 to 30 of about 164,635 (296)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

ÚLOHA MULTILATERACE PŘI ZVYŠOVANÍ BEZPEČNOSTI LETECKÉ DOPRAVY

open access: yesPerner’s Contacts, 2011
Článek popisuje využití multilateračních systémů pro zvýšení bezpečnosti a kapacity v letecké dopravy. Práce zahrnuje popis principu činnosti multilateračních systémů v závislosti na časových architekturách. Závěr práce je věnován WAM systémům.
Marcela Ujcová
doaj  

IAVCEI: from small beginnings to a vibrant international association [PDF]

open access: yesHistory of Geo- and Space Sciences, 2019
The International Association for Volcanology and Chemistry of the Earth's Interior (IAVCEI) was formed following the end of World War I at the inaugural general assembly (GA) of the International Research Council in Brussels in 1919, where the ...
R. A. F. Cas, R. A. F. Cas
doaj   +1 more source

THE END OF ART AND PATOČKA’S PHILOSOPHY OF ART [PDF]

open access: yes, 2016
In this essay I consider the end-of-art thesis in its metaphysical and empirical versions. I show that both use the correspondence theory of truth as the basis for their conception of the history of art.
Jan, Josl
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Zao čas u verovanju slovenskih naroda
«Neroven», «lih čas» v pover'jah slavjanskih narodov

open access: yesStudia Mythologica Slavica, 2011
According to the Slavic beliefs, during the circulation of the time, at the shift between the night and the day, there is a dangerous interlude, when the man is exposed to the possibility of misfortunate accident or even death.
Ljubinko Radenković
doaj   +1 more source

Populismus in Europa: Von den Rändern zum Mainstream

open access: yesTotalitarismus und Demokratie, 2020
Despite the enormous growth of academic interest during the past years, there is still significantly more known about the consequences than the causes of populism. This issue can be addressed by analyzing not only
Cas Mudde
doaj   +1 more source

Vegetation requirements of the black grouse habitat (Tetrao Tetrix L.) in Pohorje MTS. [PDF]

open access: yes, 2017
Ruševec se na Pohorju (severno-vzhodna Slovenija) pojavlja na grebenskih legahv zahodnem delu pogorja. V rastitvenih sezonah 2000 in 2001 smo napravilipopis aktivnosti sub-populacij na šestih znanih rastiščih in tako izločili ploskve potencialnega ...
Adamič, Miha   +3 more
core  

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