Results 51 to 60 of about 161,702 (247)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Slovansko-st. indijska izoglosa za pojem “čas”
Linguistica, 1971 F. Bezlaj v rokopisu svoje kritike Skokovega etimološkega slovarja sbh. jezika, ki bo izšla predvidoma v Etimologiji VII, Moskva, navaja sbh. dial. čelo »dan, dvanajst ur«, dani noc su dva čela (Risanj, Boka Kotorska) in v Črni gori kolje »Zeit, freie ...
Varja Cvetko
doaj +1 more source
Information in the Context of Philosophy and Cognitive Sciences [PDF]
, 2013 This textbook briefly maps as many as possible areas and contexts in which information plays an important role. It attempts an approach that also seeks to explore areas of research that are not commonly associated, such as informatics, information and ...
Slavkovsky, Adrian
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FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Biopotraviny, biomed a pesticidy [PDF]
, 2012 Čas od času se v médiích objeví zpráva varující spotřebitele, že potraviny obsahují pesticidy. A jak je to možné, když mají být potraviny "ekologicky čisté".
Rozsypal, Roman
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FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Setup time reduction on four-side planing machine with the SMED method [PDF]
, 2017 Zaradi čedalje hitrejšega naraščanja raznolikosti proizvodov in manjšanja velikosti izdelavnih serij je skrajšanje nastavitvenih časov na strojih ključnega pomena za dobičkonosnost podjetja.
Kropivšek, Jože +2 more
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Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
, 2009 Tato práce se zabývá barvením grafů, což je přiřazování barev jednotlivým vrcholům grafu tak, aby žádné dva vrcholy spojené hranou neměly stejnou barvu. Tento problém je velmi výpočetně náročný, protože je NP-úplný.
Procházka, Lukáš
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