Results 131 to 140 of about 7,955 (168)
ABSTRACT Background Vedolizumab is a therapeutic antibody approved for the treatment of Crohn's disease and ulcerative colitis. The population pharmacokinetics (popPK) of intravenous (IV) administered vedolizumab have been described, but remain to be defined for subcutaneous (SC) administration.
S. I. Anjie +5 more
wiley +1 more source
Abstract Carbon (δ13C) and nitrogen (δ15N) stable isotope ratios allow the reconstruction of food webs, provided that all trophic levels are properly characterized. In freshwater ecosystems, small‐bodied invertebrates often occupy central positions in food webs, with whole‐body samples commonly used for their stable isotope analysis, due to ...
Alan Fritsch +3 more
wiley +1 more source
Abstract Volunteers have been involved in nature observations for decades through citizen science initiatives, providing large data sets as well as problem identification that allow a more complete understanding of many natural phenomena. Although communication is a core component in citizen science, the key factors that determine its effectiveness in ...
Kristiina Gibson +18 more
wiley +1 more source
Mapping Psychosocial Determinants for Cancer Onset: An Umbrella Review
ABSTRACT Background Despite the growing body of literature suggesting that psychosocial factors contribute to cancer susceptibility, the existing evidence remains heterogeneous, and it is unclear which domains show the most consistent associations. Systematically mapping this literature helps inform the integration of psychosocial factors into cancer ...
M. Masiero +14 more
wiley +1 more source
We developed an invasion risk index framework that integrates socioeconomic and environmental data using an entropy‐weighting method. The case study highlights the need for region‐specific biosecurity measures for Chilo suppressalis. Abstract BACKGROUND Biological invasion risk is a multifaceted concept that, according to the Food and Agriculture ...
Jinsol Hong +11 more
wiley +1 more source
ABSTRACT Determining the credibility of population PK/PD models is a challenge, particularly when performing uncertainty quantification (UQ) for parameter estimates, which is often represented through relative standard error (RSE) values. It is important to note that RSE values are primarily based on the variance of the parameter distribution and is ...
Linda Wanika +3 more
wiley +1 more source
Giriş Kısmında; Şia ile sahih kelimelerinin tahlili, Şia fırkaları, Usûlu'l-Hadis İlmi ve Şia'da hadis ilminin doğuşu konuları ele alınmıştır. Birinci Bölümde; Şia'nın hadis/sünnet'e bakışı ile kabul ve ret açısından hadisler, ravi sayısı açısından ...
Yardak, Hasan
core
A microfluidic model of the glioblastoma (GBM) margin was developed to mimic patient‐specific blood‐brain tumor barrier (BBTB) function and drug response. The platform revealed inter‐patient variability in barrier integrity and drug sensitivity, offering a tool for personalized therapy evaluation in GBM.
Minsu Ryoo +16 more
wiley +1 more source
Anthropogenic resource subsidies can drive mesopredator population growth, altering predator–prey dynamics. The red fox Vulpes vulpes is a generalist canid that can readily exploit such subsidies. In the UK, tens of millions of pheasants Phasianus colchicus and red‐legged partridges Alectoris rufa are released annually for sport shooting, potentially ...
Nathan F. Williams +4 more
wiley +1 more source

