Results 11 to 20 of about 36,674 (196)
Ars & Humanitas, 2012 O tem, ali je šport »neresen« pojav ali pojav, ki razkriva bistvene razsežnosti tistega, za kar človeku gre, se pogledi razhajajo. Glede na to, da so humanistične študije športa vsaj na prvi pogled nekje na obrobju ved, ki jih združuje Filozofska ...
Jože Vogrinc, Lev Kreft
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Zaračunavanje nadomestil za vzgojo mladih amaterskih športnikov (vrednotni vidik pravnih pravil)
Zbornik Znanstvenih Razprav, 2020 Posameznik v družbi pripada različnim družbenim skupinam. Te si s pravnimi pravili urejajo lasten okvir delovanja. Posledice teh pravil lahko v nekaterih življenjskih situacijah vplivajo tudi zunaj družbene skupine, ki je sprejela posamično pravilo ...
Rožle Prezelj
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Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
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Mestno okolje, njegove nevarnosti in človeško vedenje [PDF]
Urbani Izziv, 1999 Fizično okolje je samo sredstvo, posrednik ali kraj uresničevanja medčloveških odnosov. To je še najbolj očitno, kadar gre za nevarnosti, s katerimi se ljudje v okolju soočajo.
Marko Polič
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
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FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
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Vračanje športnika v proces treniranja po prebolelem covidu-19
Zdravniški Vestnik, 2021 Večina športnikov s covidom-19 nima simptomov ali pa ima blage simptome, a vse več je primerov, ko simptomi vztrajajo še nekaj tednov do mesecev po okužbi. Najpogosteje so prizadeta dihala, vendar so lahko v sklopu sistemskega vnetja prizadeti tudi drugi
Nejc Planinc +7 more
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
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Nasilje v športu med mladimi športniki
Mednarodno Inovativno Poslovanje, 2023 Nasilje, kot neprimerna oblika vedenja, se vse bolj pojavlja tudi v športu. Vsepogostejše pojavljanje nasilja v športu je posledica aktualnih družbeno - ekonomskih razmer in predvsem poveličevanje pomena zmage, ki postaja pomembnejša od izvornega pomena ...
Nika Strašek
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Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
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