Results 51 to 60 of about 358,589 (291)

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Anxiety, Self-Esteem and Coping With Stress in Secondary School Students in Relation to Involvement in Organized Sports / Anksioznost, Samospoštovanje In Spoprijemanje S Stresom Pri Srednješolcih V Povezavi Z Vključenostjo V Organizirano Športno Aktivnost

open access: yesSlovenian Journal of Public Health, 2015
Cilj. Namen raziskave je bil preučiti raven samospoštovanja in anksioznosti ter uporabo različnih strategij spoprijemanja s stresom pri srednješolskih mladostnikih v povezavi z vključenostjo v redno in organizirano športno vadbo.
Dolenc Petra
doaj   +1 more source

Dejavniki gibalne aktivnosti in z zdravjem povezane kakovosti življenja

open access: yesObzornik zdravstvene nege, 2014
Uvod: Gibalna aktivnost koristi telesnemu in duševnemu zdravju. Namen članka je ugotoviti dejavnike, ki vplivajo nanjo, in možne ukrepe za povečanje te dejavnosti.
Renata Slabe Erker, Simon Ličen
doaj   +1 more source

Adolescent Sport Participation and Symptoms of Anxiety and Depression: A Systematic Review and Meta-Analysis.

open access: yesJournal of Sport & Exercise Psychology (JSEP), 2020
Sport may protect against symptoms of mental disorders that are increasingly prevalent among adolescents. This systematic review explores the relationship between adolescent organized sport participation and self-reported symptoms of anxiety and ...
Michael J. Panza   +5 more
semanticscholar   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Analysis of Injuries Among Children in Kindergartens During Physical Activities

open access: yesSlovenian Journal of Public Health, 2014
Izhodišča. Namen raziskave je bil analizirati mnenja vzgojiteljev o nastanku poškodbe pri organiziranih in neorganiziranih gibalnih dejavnostih otrok v vrtcih glede na starost otrok. Metode.
Videmšek Mateja   +5 more
doaj   +1 more source

Accuracy of human motion capture systems for sport applications; state-of-the-art review

open access: yesEuropean Journal of Sport Science, 2018
Objective: Sport research often requires human motion capture of an athlete. It can, however, be labour-intensive and difficult to select the right system, while manufacturers report on specifications which are determined in set-ups that largely differ ...
Eline van der Kruk, M. M. Reijne
semanticscholar   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Review on Wearable Technology Sensors Used in Consumer Sport Applications

open access: yesItalian National Conference on Sensors, 2019
This review paper discusses the trends and projections for wearable technology in the consumer sports sector (excluding professional sport). Analyzing the role of wearable technology for different users and why there is such a need for these devices in ...
Gobinath Aroganam   +2 more
semanticscholar   +1 more source

Toward an Integrated Understanding of the Youth Sport System

open access: yesResearch Quarterly for Exercise and Sport, 2020
The aim of the present article is to outline a heuristic model that facilitates movement toward an integrated understanding of the youth sport system. We define the youth sport system as the set of interdependent persons and contexts that influence and ...
T. Dorsch   +7 more
semanticscholar   +1 more source

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