Relation of Serum α-Amylase Level With Glycated Hemoglobin and Trace Elements in Patients With Diabetes Mellitus. [PDF]
Mahmud DA +5 more
europepmc +1 more source
IL‐22Rα1 restrains pancreatic injury independently of its C‐terminal STAT3‐amplifying domain
IL‐22R, and to a lesser extent IL‐22, are key drivers of protection in acute pancreatitis. Although the C‐terminal domain of IL‐22R enhances STAT3 activation in the pancreas, it is not required for disease protection. Classical IL‐22R signaling alone is sufficient to control inflammation and promote pancreatic recovery.
Léna Puigdevall +4 more
wiley +1 more source
Safety evaluation of an extension of use of the food enzyme α-amylase from the genetically modified <i>Bacillus licheniformis</i> strain NZYM-BC. [PDF]
EFSA Panel on Food Enzymes (FEZ) +15 more
europepmc +1 more source
Combination Pharmacotherapies for Obesity—Current Evidence and Future Directions
Combination pharmacotherapy for obesity can enhance weight loss by targeting complementary neuroendocrine and metabolic pathways. Such benefits are largely additive but limited by tolerability, cost and access. This review outlines practical clinical archetypes and a research agenda for safer, more precise and durable combination strategies across ...
A. B. M. Kamrul‐Hasan +6 more
wiley +1 more source
Study on the Inhibitory Mechanisms of Native Cellulose, Microcrystalline Cellulose, and Soluble Cellodextrin on α-Amylase and Amyloglucosidase. [PDF]
Zhu Y +7 more
europepmc +1 more source
ABSTRACT Consumption of whole wheat flour promotes lead excretion, yet the functional components reducing lead bioavailability and their protective mechanisms remain unclear. To identify these components and to validate whether their mechanism is related to protection of the intestinal barrier, this study established an in vitro model combining ...
Zhiyin Xiao +7 more
wiley +1 more source
Synthesis of Some Novel Chalcone and 3,5-Disubstituted Pyrazoline Derivatives: Evaluation of Their α-Amylase and α-Glucosidase Inhibitory Activities In Vitro and In Silico. [PDF]
Erbay F +6 more
europepmc +1 more source
Intelligent design of artificial biocatalyst for biomedical diseases
This review summarizes recent advances in the intelligent design of artificial biocatalysts for biomedical diseases. By leveraging tailored design strategies, including environment‐responsive engineering and rational/artificial intelligence‐aided optimization, these biocatalysts enable precise modulation of pathological microenvironments and targeted ...
Lijie Zhang +3 more
wiley +1 more source
HPTLC based screening method for the evaluation of α-amylase inhibitory activity in edible flowers. [PDF]
Litewski S, Mróz M, Kusznierewicz B.
europepmc +1 more source
ABSTRACT Chickpea (Cicer arietinum L.) is an important dietary legume worldwide and provides micronutrients and phytochemicals, including phenolics, flavonoids, carotenoids, bioactive peptides, dietary fiber, and resistant starch. This narrative review summarizes evidence from in vitro, animal, and human studies on the potential health relevance of ...
Rohama Shahid +4 more
wiley +1 more source

