Results 1 to 10 of about 789,557 (313)

Serum α-Glucosidase Activity as a New Parameter of Negative Energy Balance in Dairy Cows [PDF]

open access: yesVeterinary Sciences
Enzymes of the α-glucosidase group cleave α-D-glucose from the non-reducing end of short oligosaccharides. They contribute to carbohydrate digestion as maltase-glucoamylase in the intestinal brush border and as neutral α-glucosidase in other tissues ...
Babett Bartling   +3 more
doaj   +2 more sources

Advances in the natural α‐glucosidase inhibitors

open access: yeseFood, 2023
α‐Glucosidase (AG) inhibitors, one of the classes of oral antidiabetics used to treat type 2 diabetes mellitus, delay digestion and absorption of glucose, which in turn, has a lowering effect on postprandial blood glucose and insulin levels.
Didem Şöhretoğlu   +4 more
doaj   +1 more source

Screening and functional evaluation of the glucose-lowering active compounds of total saponins of Baibiandou (Lablab Semen Album)

open access: yesDigital Chinese Medicine, 2021
Objective: To screen for α-glucosidase inhibitor active compounds in the total saponins of Baibiandou (Lablab Semen Album) based on UHPLC-Q-Exactive Orbitrap MS technology and to evaluate its hypoglycemic activity in vivo.
Jun Han   +3 more
doaj   +1 more source

β-Glucosidase from the cellulolytic system of Alternaria alternata autolyzed cultures [PDF]

open access: yesFEMS Microbiology Letters, 1988
A β-glucosidase from centrifugated autolyzed cultures of Alternaria alternata has been purified 71 times by Sephadex G-200, CM-Biogel A and DEAE-Biogel A successively. The enzyme is a glycoprotein with 16% sugar and a Mr of 160 000, formed by two subunits of 60 000 and 80 000.
María Jesús Martínez   +3 more
openaire   +1 more source

Design, synthesis, in vitro, and in silico biological evaluations of coumarin-indole hybrids as new anti-α-glucosidase agents

open access: yesBMC Chemistry, 2022
Background A series of coumarin-indole hybrids was synthesized as the new α-glucosidase inhibitors. The title hybrids were considered as α-glucosidase inhibitors because had two active pharmacophores against α-glucosidase: coumarin and indole.
Davood Rezapour Niri   +9 more
doaj   +1 more source

A constitutive, plasma-membrane bound β-glucosidase inTrichoderma reesei [PDF]

open access: yesFEMS Microbiology Letters, 1986
Plasma membranes of Trichoderma reesei QM 9414, isolated from protoplasts by means of the concanavalin A procedure, contained β-glucosidase activity, which appeared constitutively upon growth on glucose. The enzyme had a pH optimum around 6, and was active on p-nitrophenyl-β-d-glucoside, cellobiose and sophorose (Km 0.7, 3.9 and 3.1 mM, respectively ...
Claudio Umile, Christian P. Kubicek
openaire   +1 more source

α-glucosidase inMycoplasma mycoidessubspeciescapri [PDF]

open access: yesFEMS Microbiology Letters, 1988
Mycoplasma mycoides subsp. capri utilisede maltose in medium lacking serum and hence serum saccharolytic enzymes. The presence of α-glucosidase activity was demonstrated by p-nitrophenyl-α-d-glucoside hydrolysis in toluene-treated cells. Specific activities were approx.
B.J. Wadher, R.J. Miles
openaire   +1 more source

Synthesis of activity evaluation of flavonoid derivatives as ɑ-glucosidase inhibitors

open access: yesFrontiers in Chemistry, 2022
Six flavonoid derivatives were synthesized and tested for anti-α-glucosidase activities. All derivatives were confirmed using NMR and HRMS and exhibited excellent inhibitory effects on α-glucosidase.
Hua Zhu, Xin Zhong
doaj   +1 more source

Enhanced enzymatic activity and stability by in situ entrapment of α-Glucosidase within super porous p(HEMA) cryogels during synthesis

open access: yesBiotechnology Reports, 2020
Here, poly(2-hydroxyethyl methacrylate) (p(HEMA)) cryogel were prepared in the presence 0.48, 0.96, and 1.92 mL of α-Glucosidase enzyme (0.06 Units/mL) solutions to obtain enzyme entrapped superporous p(HEMA) cryogels, donated as α-Glucosidase@p(HEMA)-1,
Sahin Demirci   +4 more
doaj   +1 more source

Identification and Molecular Binding Mechanism of Novel α-Glucosidase Inhibitory Peptides from Hot-Pressed Peanut Meal Protein Hydrolysates

open access: yesFoods, 2023
Hot-pressed peanut meal protein hydrolysates are rich in Arg residue, but there is a lack of research on their α-glucosidase inhibitory activity. In this study, different proteases were used to produce hot-pressed peanut meal protein hydrolysates (PMHs ...
Xinyu Yang   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy