Results 1 to 10 of about 1,799,019 (357)
Foods, 2023 Hot-pressed peanut meal protein hydrolysates are rich in Arg residue, but there is a lack of research on their α-glucosidase inhibitory activity. In this study, different proteases were used to produce hot-pressed peanut meal protein hydrolysates (PMHs ...
Xinyu Yang +5 more
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Journal of Enzyme Inhibition and Medicinal Chemistry, 2022 Different oleanolic acid (OA) oxime ester derivatives (3a-3t) were designed and synthesised to develop inhibitors against α-glucosidase and α-amylase. All the synthesised OA derivatives were evaluated against α-glucosidase and α-amylase in vitro.
Xu-Yang Deng +9 more
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Serum α-Glucosidase Activity as a New Parameter of Negative Energy Balance in Dairy Cows [PDF]
Veterinary SciencesEnzymes of the α-glucosidase group cleave α-D-glucose from the non-reducing end of short oligosaccharides. They contribute to carbohydrate digestion as maltase-glucoamylase in the intestinal brush border and as neutral α-glucosidase in other tissues ...
Babett Bartling +3 more
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In vitro α-glucosidase inhibitory activity of Tamarix nilotica shoot extracts and fractions.
PLoS ONE, 2022 α-glucosidase inhibitors represent an important class of type 2 antidiabetic drugs and they act by lowering postprandial hyperglycemia. Today, only three synthetic inhibitors exist on the market, and there is a need for novel, natural and more efficient ...
Mariane Daou +5 more
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A review on the in vitro and in vivo screening of α-glucosidase inhibitors
HeliyonAs a global metabolic disease, the control and treatment of diabetes have always been the focus of medical research. α-Glucosidase is a key enzyme in regulating blood glucose levels and has important applications in the treatment of diabetes. This review
Guangjuan Pan +5 more
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Advances in the natural α‐glucosidase inhibitors
eFood, 2023 α‐Glucosidase (AG) inhibitors, one of the classes of oral antidiabetics used to treat type 2 diabetes mellitus, delay digestion and absorption of glucose, which in turn, has a lowering effect on postprandial blood glucose and insulin levels.
Didem Şöhretoğlu +4 more
doaj +1 more source
Digital Chinese Medicine, 2021 Objective: To screen for α-glucosidase inhibitor active compounds in the total saponins of Baibiandou (Lablab Semen Album) based on UHPLC-Q-Exactive Orbitrap MS technology and to evaluate its hypoglycemic activity in vivo.
Jun Han +3 more
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α-glucosidase inMycoplasma mycoidessubspeciescapri [PDF]
FEMS Microbiology Letters, 1988 Mycoplasma mycoides subsp. capri utilisede maltose in medium lacking serum and hence serum saccharolytic enzymes. The presence of α-glucosidase activity was demonstrated by p-nitrophenyl-α-d-glucoside hydrolysis in toluene-treated cells. Specific activities were approx.
B.J. Wadher, R.J. Miles
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β-Glucosidase from the cellulolytic system of Alternaria alternata autolyzed cultures [PDF]
FEMS Microbiology Letters, 1988 A β-glucosidase from centrifugated autolyzed cultures of Alternaria alternata has been purified 71 times by Sephadex G-200, CM-Biogel A and DEAE-Biogel A successively. The enzyme is a glycoprotein with 16% sugar and a Mr of 160 000, formed by two subunits of 60 000 and 80 000.
MarÃa Jesús MartÃnez +3 more
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BMC Chemistry, 2022 Background A series of coumarin-indole hybrids was synthesized as the new α-glucosidase inhibitors. The title hybrids were considered as α-glucosidase inhibitors because had two active pharmacophores against α-glucosidase: coumarin and indole.
Davood Rezapour Niri +9 more
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