Results 31 to 40 of about 1,799,019 (357)

Acantholippia salsoloides : Phytochemical Composition and Biological Potential of a Thujonic Population [PDF]

open access: yes, 2019
Acantholippia salsoloides (Verbenaceae) is an aromatic plant widespread in the Andean region. The infusion (leaves and flowers) is widely used as a digestive stimulant as well as for the treatment of various diseases in traditional medicine.
Celaya, Liliana Soledad   +2 more
core   +1 more source

Synthesis and Evaluation of Coumarin-Chalcone Derivatives as α-Glucosidase Inhibitors

open access: yesFrontiers in Chemistry, 2022
Coumarin and chalcone, two important kinds of natural product skeletons, both exhibit α-glucosidase inhibitory activity. In this work, coumarin-chalcone derivatives 3 (a∼v) were synthesized, and their α-glucosidase inhibitory activity was screened.
Chun-Mei Hu   +10 more
doaj   +1 more source

Inhibition activity of α-glucosidase by infusion and ethanol extract of white tea and stevia combination [PDF]

open access: yesJurnal Sains Teh dan Kina, 2017
Ethanol extract of white tea and its stevia liquor was observed for α-glukosidase inhibition. The research was divided into some steps;  white tea and stevia combination hedonic sensory test, phytochemical identification, and α-glucosidase inhibition activity.
Elvi Trinoviani   +3 more
openaire   +1 more source

New quinoline-based triazole hybrid analogs as effective inhibitors of α-amylase and α-glucosidase: Preparation, in vitro evaluation, and molecular docking along with in silico studies

open access: yesFrontiers in Chemistry, 2022
The 7-quinolinyl-bearing triazole analogs were synthesized (1d–19d) and further assessed in vitro for their inhibitory profile against α-amylase andα-glucosidase. The entire analogs showed a diverse range of activities having IC50 values between 0.80 ± 0.
Yousaf Khan   +11 more
semanticscholar   +1 more source

Properties and stabilization of an extracellular α-glucosidase from the extremely thermophilic archaebacteria Thermococcus strain AN 1: enzyme activity at 130°C [PDF]

open access: yes, 1996
An extracellular α-glucosidase from the thermophilic archaebacterium Thermococcus strain AN1 was purified 875-fold in five steps (Hiload Q-Sepharose, phenyl Sepharose, HPHT-hydroxyapatite, gel filtration and Mono Q chromatography) with a yield of 4%.
Daniel, Roy M.   +2 more
core   +2 more sources

Docking Sulochrin and Its Derivative as α-Glucosidase Inhibitors of Saccharomyces cerevisiae

open access: yesIndonesian Journal of Chemistry, 2017
Sulochrin known has activity as inhibitors of α-glucosidase enzyme. Interaction of sulochrin to active site of α-glucosidase enzyme from S. cerevisiae has studied by docking method.
Wening Lestari   +3 more
doaj   +1 more source

Design, Synthesis, In Silico Testing, and In Vitro Evaluation of Thiazolidinone-Based Benzothiazole Derivatives as Inhibitors of α-Amylase and α-Glucosidase

open access: yesPharmaceuticals, 2022
In this study, a stepwise reaction afforded thiazolidinone-based benzothiazole derivatives 1–15, and the synthesized derivatives were then screened for biological significance and found to be the leading candidates against α-amylase and α-glucosidase ...
Shoaib Khan   +11 more
semanticscholar   +1 more source

Influence of preparation procedures on the phenolic content, antioxidant and antidiabetic activities of green and black teas [PDF]

open access: yes, 2019
The influence of common tea preparation procedures (temperature, infusion time, consumption time interval and tea bag/loose-leaf) and the type of water used, on the total phenolic content (TPC), the radical scavenging activity and the alpha-glucosidase ...
Almeida, Tânia Santos de   +6 more
core   +3 more sources

An overview on the role of bioactive α-glucosidase inhibitors in ameliorating diabetic complications

open access: yesFood and Chemical Toxicology, 2020
Recently the use of bioactive α-glucosidase inhibitors for the treatment of diabetes have been proven to be the most efficient remedy for controlling postprandial hyperglycemia and its detrimental physiological complications, especially in type 2 ...
Uday Hossain   +3 more
semanticscholar   +1 more source

In Silico Approaches to Identify Polyphenol Compounds as α-Glucosidase and α-Amylase Inhibitors against Type-II Diabetes

open access: yesBiomolecules, 2021
Type-II diabetes mellitus (T2DM) results from a combination of genetic and lifestyle factors, and the prevalence of T2DM is increasing worldwide. Clinically, both α-glucosidase and α-amylase enzymes inhibitors can suppress peaks of postprandial glucose ...
Jirawat Riyaphan   +3 more
semanticscholar   +1 more source

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