Results 31 to 40 of about 1,767,652 (263)
Inhibition activity of α-glucosidase by infusion and ethanol extract of white tea and stevia combination [PDF]
Jurnal Sains Teh dan Kina, 2017 Ethanol extract of white tea and its stevia liquor was observed for α-glukosidase inhibition. The research was divided into some steps;  white tea and stevia combination hedonic sensory test, phytochemical identification, and α-glucosidase inhibition activity.
Elvi Trinoviani +3 more
openaire +1 more source
Journal of Enzyme Inhibition and Medicinal Chemistry, 2022 Different oleanolic acid (OA) oxime ester derivatives (3a-3t) were designed and synthesised to develop inhibitors against α-glucosidase and α-amylase. All the synthesised OA derivatives were evaluated against α-glucosidase and α-amylase in vitro.
Xu-Yang Deng +9 more
doaj +1 more source
Food Chemistry, 2021 Phenolic acids are involved in modulating the activity of starch digestive enzymes but remains unclear if their interaction with enzymes or starch is governing the inhibition.
Andrea Aleixandre +3 more
semanticscholar +1 more source
Molecules, 2023 To find potential α-glucosidase inhibitors, indolo[1,2-b]isoquinoline derivatives (1–20) were screened for their α-glucosidase inhibitory effects. All derivatives presented potential α-glucosidase inhibitory effects with IC50 values of 3.44 ± 0.36~41.24 ±
Mengyue Li +5 more
doaj +1 more source
Frontiers in Chemistry, 2022 α-Glucosidase inhibitors are known to prevent the digestion of carbohydrates and reduce the impact of carbohydrates on blood glucose. To develop novel α-glucosidase inhibitors, a series of 5-fluoro-2-oxindole derivatives (3a ∼ 3v) were synthesized, and ...
Jing Lin +10 more
doaj +1 more source
MCBS (Molecular and Cellular Biomedical Sciences), 2017 Background: Diabetes mellitus is a metabolic disease, characterized by hyperglycemia due to disturbance in both insulin secretion and function. One of theurapeutic approaches is to reduce blood glucose levels by inhbiting α-/β-glucosidase and α-amylase ...
Marisca Evalina Gondokesumo +2 more
doaj +1 more source
Bangladesh Journal of Pharmacology, 2013 In this study, the effect of ethanol extract of the leaves of Newbouldia laevis on the activity of α-amylase and α-glucosidase was investigated. Inhibitory effect of N. laevis extract on α-glucosidase was tested in vitro using baker's yeast α-glucosidase
Oyetunji T. Kolawole, Musbau A. Akanji
doaj +1 more source
Molecules, 2023 Current antidiabetic drugs have severe side effects, which may be minimized by new selective molecules that strongly inhibit α-glucosidase and weakly inhibit α-amylase.
Dolores G. Aguila-Muñoz +10 more
doaj +1 more source
Synthesis and Evaluation of Coumarin-Chalcone Derivatives as α-Glucosidase Inhibitors
Frontiers in Chemistry, 2022 Coumarin and chalcone, two important kinds of natural product skeletons, both exhibit α-glucosidase inhibitory activity. In this work, coumarin-chalcone derivatives 3 (a∼v) were synthesized, and their α-glucosidase inhibitory activity was screened.
Chun-Mei Hu +10 more
doaj +1 more source
The α-Amylase and α-Glucosidase Inhibition Capacity of Grape Pomace: A Review
Food and Bioprocess Technology, 2022 The concept of functional foods is gaining more importance due to its role in maintaining a healthy status and preventing some metabolic diseases. The control of diabetes, in particular type-2 (T2DM), could be considered a big challenge since it involves
Miluska Cisneros‐Yupanqui +4 more
semanticscholar +1 more source