Results 21 to 30 of about 1,799,019 (357)
Inhibitory Activity and Mechanism Investigation of Hypericin as a Novel α-Glucosidase Inhibitor
Molecules, 2021 α-glucosidase is a major enzyme that is involved in starch digestion and type 2 diabetes mellitus. In this study, the inhibition of hypericin by α-glucosidase and its mechanism were firstly investigated using enzyme kinetics analysis, real-time ...
Qi Dong, Na Hu, Huilan Yue, Honglun Wang
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Pomegranate ellagitannins inhibit α-glucosidase activity in vitro and reduce starch digestibility under simulated gastro-intestinal conditions [PDF]
, 2014 Pomegranate extract was tested for its ability to inhibit α-amylase and α-glucosidase activity. Pomegranate extract strongly inhibited rat intestinal α-glucosidase in vitro whereas it was a weak inhibitor of porcine α-amylase. The inhibitory activity was
BELLESIA, ANDREA +2 more
core +1 more source
Molecules, 2023 To find potential α-glucosidase inhibitors, indolo[1,2-b]isoquinoline derivatives (1–20) were screened for their α-glucosidase inhibitory effects. All derivatives presented potential α-glucosidase inhibitory effects with IC50 values of 3.44 ± 0.36~41.24 ±
Mengyue Li +5 more
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The α-Amylase and α-Glucosidase Inhibition Capacity of Grape Pomace: A Review
Food and Bioprocess Technology, 2022 The concept of functional foods is gaining more importance due to its role in maintaining a healthy status and preventing some metabolic diseases. The control of diabetes, in particular type-2 (T2DM), could be considered a big challenge since it involves
Miluska Cisneros‐Yupanqui +4 more
semanticscholar +1 more source
Frontiers in Chemistry, 2022 α-Glucosidase inhibitors are known to prevent the digestion of carbohydrates and reduce the impact of carbohydrates on blood glucose. To develop novel α-glucosidase inhibitors, a series of 5-fluoro-2-oxindole derivatives (3a ∼ 3v) were synthesized, and ...
Jing Lin +10 more
doaj +1 more source
Flavonoids with α-glucosidase inhibitory activities and their contents in the leaves of Morus atropurpurea [PDF]
, 2013 BACKGROUND: This study aims to isolate the α-glucosidase inhibitory compounds from mulberry leaves (Morus atropurpurea Roxb., Moraceae) and to develop an analytical method for quantification of the compounds.
Hin-Chu Hong +4 more
core +1 more source
MCBS (Molecular and Cellular Biomedical Sciences), 2017 Background: Diabetes mellitus is a metabolic disease, characterized by hyperglycemia due to disturbance in both insulin secretion and function. One of theurapeutic approaches is to reduce blood glucose levels by inhbiting α-/β-glucosidase and α-amylase ...
Marisca Evalina Gondokesumo +2 more
doaj +1 more source
Molecules, 2023 Current antidiabetic drugs have severe side effects, which may be minimized by new selective molecules that strongly inhibit α-glucosidase and weakly inhibit α-amylase.
Dolores G. Aguila-Muñoz +10 more
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In-Vitro α-Glucosidase Inhibitory Activities of Muntingia Calabura Linn.
International Journal of Engineering & Technology, 2019 Muntingia calabura Linn. also known locally as “ceri kampung†is a plant of the family Elaeocarpaceae. The plant has been reported to possess several medicinal properties including reducing high blood pressure, lowering cholesterol level and controlling Type 2 diabetes.
N I.I. Nor Azman, N Hashim, R Ahmad
openaire +2 more sources
Bangladesh Journal of Pharmacology, 2013 In this study, the effect of ethanol extract of the leaves of Newbouldia laevis on the activity of α-amylase and α-glucosidase was investigated. Inhibitory effect of N. laevis extract on α-glucosidase was tested in vitro using baker's yeast α-glucosidase
Oyetunji T. Kolawole, Musbau A. Akanji
doaj +1 more source