Results 51 to 60 of about 996,086 (243)

AS‐pHopt: An Optimal pH Prediction Model Enhanced by Active Site of Enzymes

Advanced Intelligent Discovery, EarlyView.
To address the low accuracy of enzyme optimal pH (pHopt) prediction, this study develops active site‐based pHopt (AS‐pHopt), a prediction model enhanced by active site information and pseudo‐label prediction. Integrating key structural and physicochemical features affecting enzyme pHopt, AS‐pHopt uses Evolutionary Scale Modeling (ESM)‐2 with active ...
Wenxiang Song, Xinmin Li, Hongbo Yu, Le Xiong, Guixia Liu, Weihua Li, Yun Tang   +6 more
wiley   +1 more source

Innervation of the tubarial glands: A hypothesis‐driven anatomical review

The Anatomical Record, EarlyView.
Abstract The tubarial glands have been described as a macroscopic bilateral glandular complex in the posterolateral nasopharynx near the torus tubarius and the pharyngeal opening of the Eustachian tube. Since their recognition on prostate‐specific membrane antigen‐based imaging, their anatomical classification has remained debated, with converging ...
Mugurel Constantin Rusu, Ivan Varga, Răzvan Costin Tudose   +2 more
wiley   +1 more source

Synthesis of Benzylidene Analogs of Oleanolic Acid as Potential α-Glucosidase and α-Amylase Inhibitors

Frontiers in Chemistry, 2022
A series of benzylidene analogs of oleanolic acid 4a∼4s were synthesized and assessed for their α-glucosidase and α-amylase inhibitory activities. The results presented that all synthesized analogs exhibited excellent-to-moderate inhibitory effects on α ...
Jun-Jie Ke, Jing Lin, Xin Zhang, Xiao-Zheng Wu, Ying-Ying Zheng, Chun-Mei Hu, Yu Kang, Kun Zhang, Zhuang Xiong, Zhi-Qiang Ma   +9 more
doaj   +1 more source

α-Amylase Inhibitory Triterpene fromAbrus precatoriusLeaves [PDF]

, 2014
In the screening experiments for porcine pancreatic α-amylase inhibitors in 18 plants obtained from Indonesia, a potent inhibitory activity was detected in the extract of leaves of Abrus precatorius.
Yonemoto, Ryuta, Kato, Eisuke, Shimada, Miyuki, Kawabata, Jun, Gunawan-Puteri, Maria D. P. T.   +4 more
core   +1 more source

Heat Stress and Gut Microbiome Dynamics in Poultry: Interplay, Consequences, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke, A. I. Oni, O. A. Akosile, K. M. Oliyide, C. A. Ishola, M. O. Logunleko, O. A. Jimoh, C. P. Njoku, L. O. Fasasi, V. A. Uyanga   +9 more
wiley   +1 more source

In Vitro Inhibitory Effects of Cyandin-3-rutinoside on Pancreatic α-Amylase and Its Combined Effect with Acarbose

Molecules, 2011
The inhibitory activity on pancreatic α-amylase by cyanidin-3-rutinoside was examined in vitro. The IC50 value of cyanidin-3-rutinoside against pancreatic α-amylase was 24.4 ± 0.1 μM.
Sarinya Akkarachiyasit, Sirintorn Yibchok-Anun, Sumrit Wacharasindhu, Sirichai Adisakwattana   +3 more
doaj   +1 more source

In vitro, in silico and Pharmaco-toxicological Efficiencies of some Triazole Derivatives on Inhibition of Digestive Enzyme Alpha-amylase

Brazilian Archives of Biology and Technology, 2022
Obesity is one of the main health problems associated with a range of diseases. Genetic disposition is related to the risk for obesity but external conditions such lifestyle also increase the incidence.
Elif Ayazoglu Demir, Ahmet Colak, Selcen Celik Uzuner, Ahmet Yasar, Olcay Bekircan, Aylin Kabahasanoglu   +5 more
doaj   +1 more source

Impact of exogenous maltogenic α-amylase and maltotetraogenic amylase on sugar release in wheat bread [PDF]

, 2021
The use of exogenous maltogenic α-amylases or maltotetraogenic amylases of bacterial origin is common in wheat bread production, mainly as antistaling agents to retard crumb firming.
Dirndorfer, Sebastian, Sebald, Karin, Dawid, Corinna, Scherf, Katharina Anne, Hofmann, Thomas, Rebholz, Gerold Felix   +5 more
core   +1 more source

Gut Health in Ostriches (Struthio camelus): Insights Into Intestinal Structure, Functions, Microbiome, and Improvement Strategies

Animal Research and One Health, EarlyView.
Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang, Fang‐Fang Guo, Wen‐Juan Du, Meng Li, Aftab Shaukat, Zhu‐Qing Jia, Shu‐Cheng Huang   +6 more
wiley   +1 more source

Genomic and functional characterization of coleopteran insect-specific α-amylase inhibitor gene from Amaranthus species

, 2017
The smallest 32 amino acid α-amylase inhibitor from Amaranthus hypochondriacus (AAI) is reported. The complete gene of pre-protein (AhAI) encoding a 26 amino acid (aa) signal peptide followed by the 43 aa region and the previously identified 32 aa ...
Amey J. Bhide, Ashok P. Giri, Vidya S. Gupta, Gupta, Vidya S., V. L. Maheshwari, Giri, Ashok P., Kabita Bhattacharjee, Channale, Sonal M., Yashpal Yadav, Pankaj K. Pawar, Pawar, Pankaj K., Ramasamy, Sureshkumar, Bhide, A., Maheshwari, V. L., Sureshkumar Ramasamy, Yadav, Yashpal, Sonal M. Channale, Bhattacharjee, Kabita   +17 more
core   +1 more source