Results 41 to 50 of about 36,507 (220)

On the Classical Paranormed Sequence Spaces and Related Duals over the Non-Newtonian Complex Field

open access: yesJournal of Function Spaces, 2015
The studies on sequence spaces were extended by using the notion of associated multiplier sequences. A multiplier sequence can be used to accelerate the convergence of the sequences in some spaces.
Uğur Kadak   +2 more
doaj   +1 more source

On the Domain of the Four-Dimensional Sequential Band Matrix in Some Double Sequence Spaces

open access: yesMathematics, 2020
Let E represent any of the spaces M u , C ϑ ( ϑ = { b , b p , r } ) , and L q ( 0
Orhan Tuğ   +2 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Some Topological and Geometric Properties of Some New Spaces of λ-Convergent and Bounded Series

open access: yesJournal of Function Spaces, 2015
The main purpose of this study is to introduce the spaces csλ, cs0λ, and bsλ which are BK-spaces of nonabsolute type. We prove that these spaces are linearly isomorphic to the spaces cs, cs0, and bs, respectively, and derive some inclusion relations ...
Meltem Kaya, Hasan Furkan
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

α-Chloro-β,γ-ethylenic Esters: Enantiocontrolled Synthesis and Substitutions

open access: yes, 2016
Chiral nonracemic γ-seleno-α,β-ethylenic esters, when treated with sulfuryl chloride and ethyl vinyl ether in hexanes, produced α-chloro-β,γ-ethylenic esters in 65−75% yields, with ee values of 95−97%, and with 1,3-syn transfer of chirality.
Douglas T. Genna (207632)   +3 more
core   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Catalytic Enantioselective α,β,γ-Trioxygenation

open access: yes, 2015
Applying a catalytic enantioselective aldehyde α-oxygenation condition to an enal substrate led to the discovery of the first α,β,γ-trifunctionalization cascade of enals.
Gayan A. Abeykoon (1457647)   +1 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

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