Results 261 to 270 of about 90,634 (287)

Physical Fitness and Physical Function in Patients With Fabry Disease: A Cross‐Sectional Multicentre Study

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Fabry disease (FD) is a rare, X‐linked lysosomal storage disorder affecting multiple organs, including the musculoskeletal system. The physical status of FD patients remains poorly characterized. This multicentre cross‐sectional study aimed to evaluate physical fitness and function in FD patients and investigate associations with ...
Nicola Vitturi   +17 more
wiley   +1 more source

Circulating Metabolites Treat Human TMJ‐OA by Eliminating Senescent Chondrocytes via the C1QBP/C1q/p14ARF Axis

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 2, February 2026.
ABSTRACT Temporomandibular joint osteoarthritis (TMJ‐OA) is a progressive degenerative disorder, for which therapeutic interventions remain limited. The disruption of metabolic homeostasis plays a critical role in the pathogenesis and advancement of TMJ‐OA.
Bowen Meng   +19 more
wiley   +1 more source

Multi‐environment evaluation of raffinose‐family oligosaccharide content in diverse dry bean varieties and their reduction upon canning

open access: yesJournal of the Science of Food and Agriculture, Volume 106, Issue 3, Page 1904-1913, February 2026.
Abstract BACKGROUND The substantial amount of raffinose family oligosaccharide (RFO) in dry beans causes flatulence and digestive discomfort, limiting the appeal of dry bean food products. Substantial variation exists in RFO content among dry bean varieties, and various food processing steps such as soaking and canning are known to reduce RFO levels ...
Brendan M. O'Leary   +3 more
wiley   +1 more source

Activity-based metaproteomics driven discovery and enzymological characterization of potential α-galactosidases in the mouse gut microbiome

open access: gold
Jianbing Jiang   +10 more
openalex   +1 more source

Lipid Nanoparticles Delivering ClpP‐mRNA Suppress Pyroptosis and Senescence in Intervertebral Disc Degeneration via mTOR/BNIP3‐Activated Mitophagy

open access: yesRare Metals, Volume 45, Issue 2, February 2026.
ABSTRACT Intervertebral disc degeneration (IDD) is a predominant cause of low back pain, significantly impacting quality of life. Mitochondrial fitness is essential in the progression of IDD, as it regulates cellular senescence and pyroptosis. This study investigates the role of mitochondrial caseinolytic protease P (ClpP) in alleviating senescence and
Kun Wang   +7 more
wiley   +1 more source

α-galactosidase A deficiency promotes von Willebrand factor secretion in models of Fabry disease. [PDF]

open access: yesKidney Int, 2019
Kang JJ   +6 more
europepmc   +1 more source

β-Galactosidase and α-L-Arabinofuranosidase Activities and Gene Expression in European and Chinese Pear Fruit During Ripening

open access: diamond, 2007
Mercy Mwaniki   +8 more
openalex   +2 more sources

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