Results 271 to 280 of about 90,634 (287)
Small, Volume 22, Issue 11, 20 February 2026.This proteomic study examines how nanofibers affect lung macrophages by analyzing protein changes following exposure to various fibrous materials. Nanofibers triggered the release of inflammatory enzymes, and importantly, lysosomal content release was identified as an early event associated with frustrated phagocytosis. Seventeen sensitive and relevant
Tobias Stobernack +9 more
wiley +1 more source
Small Methods, Volume 10, Issue 3, 9 February 2026.Fluorophores at the peptide C‐terminus reprogram EISA behavior in osteosarcoma cellsshifting ER vs mitochondrial targeting, altering assembly, and tuning cytotoxicity. Abstract Enzyme‐instructed self‐assembly (EISA) of peptides offers a versatile strategy for developing intracellular nanomedicines, yet the role of C‐terminus fluorophores in modulating ...
Yali Huang +3 more
wiley +1 more source
Characterization of a highly stable α-galactosidase from thermophilic Rasamsonia emersonii heterologously expressed in a modified Pichia pastoris expression system. [PDF]
Microb Cell Fact, 2019 An JL, Zhang WX, Wu WP, Chen GJ, Liu WF.
europepmc +1 more source
Small Structures, Volume 7, Issue 2, February 2026.This review presents aggregation (AIE)‐induced emission materials as an integrated platform that links cancer care and fertility preservation. They detect tumors, guide surgery, and enable light‐activated therapy while monitoring reproductive health. Bright and stable signals support early diagnosis and navigation.
Yaoqin Mu, Yanbo Li, Jun Dai, Kezhen Li
wiley +1 more source
Microbial Biotechnology, Volume 19, Issue 2, February 2026.Shouchella clausii, a spore‐forming Gram‐positive bacterium with a long‐standing use as probiotic, has long been considered genetically intractable. This study introduces a high‐efficiency electroporation protocol and a versatile Golden Gate‐compatible shuttle vector (pM4B522), enabling precise, scarless and iterative genome editing in both S.
Claudia Cappella +6 more
wiley +1 more source
Yeast‐Based Biotechnology for Civilian Security
Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.Yeasts constitute robust and versatile eukaryotic platforms for biotechnological applications relevant to civilian security. Both native and genetically engineered yeast systems enable sensitive detection of chemical and biological hazards, effective removal of metals and organic pollutants, and detoxification of mycotoxins.
Justyna Ruchała +2 more
wiley +1 more source
A Novel Human Cellular System for Studying Normal Aging and for Anti‐Aging Discovery
Aging Cell, Volume 25, Issue 2, February 2026.This study introduces a human cellular aging model using placental trophoblasts (hTSC‐STBs) that mimics key aging features like senescence and genomic instability. It aligns with human tissue aging and responds to anti‐aging treatments, offering a scalable platform to screen potential therapies and bridge lab findings to clinical applications ...
Zhen Feng +14 more
wiley +1 more source
The Secretome of Human Trophoblast Stem Cells Attenuates Senescence‐Associated Traits
Aging Cell, Volume 25, Issue 2, February 2026.Human trophoblast stem cell‐derived secretome/conditioned medium (hTSC‐CM) and the extracellular vesicles (EVs) therein suppress DNA damage and NF‐κB activation in senescent fibroblasts, in turn reducing the production of senescence‐associated secretory phenotype (SASP) factors. This study highlights hTSC‐CM and EVs as potential senotherapeutic agents.
Kotb Abdelmohsen +18 more
wiley +1 more source
Hevin Promotes Aging‐Related Cardiac Dysfunction via Facilitating Cardiac Inflammation in Male Mice
Aging Cell, Volume 25, Issue 2, February 2026.Hevin released by iWAT into circulation stimulates cardiac macrophages through TLR4, inducing their polarization and CCL5 secretion, leading to worsened cardiac dysfunction and subsequent recruitment of additional inflammatory cells for pro‐inflammatory factor release.
Shi‐Yu Huang +4 more
wiley +1 more source
Aging Cell, Volume 25, Issue 2, February 2026.Unrestrained Cdc42 activity causes failure of cytotoxic function of old NK cells. This is associated with disruption of microtubular network and impaired mitochondrial ATP resulting in reduced conjugation and impaired degranulation of lytic vesicles.
Albert Kallon Koroma +15 more
wiley +1 more source