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ANTIDIABETIC ACTIVITY TEST OF BITTER GOURD EXTRACT (Momordica charantia) AS AN INHIBITOR OF α - GLUCOSIDASE ENZYME BY IN SILICO

2022
ABSTRACTDiabetes mellitus (DM) is a metabolic disorder that interferes with the metabolism of carbohydrates, fats, and proteins. This study aims to determine the types of bioactive compounds contained in bitter melon extract and to analyze interaction of targeted compounds against the α -glucosidase enzyme using the in silico approach.
Wowor, Kezya   +3 more
openaire   +1 more source

Solvent Effect on Phenolic Compounds Extraction, Antioxidant Capacities and Α-Amylase and Α-Glucosidase Inhibition of Clematis flammula and Periploca angustifolia

Journal of Pharmaceutics & Drug Delivery Research, 2016
Solvent Effect on Phenolic Compounds Extraction, Antioxidant Capacities and Α-Amylase and Α-Glucosidase Inhibition of Clematis flammula and Periploca angustifolia Abstract Phytochemicals are extensively found at different levels in many medicinal plants.
Khaled Athmouni, Taheni Belghith
openaire   +1 more source

The role of olive β-glucosidase in shaping the phenolic profile of virgin olive oil

Food Research International, 2012
The main objective of this work was to investigate the biochemical factors directly affecting the phenolic profile of virgin olive oil (VOO) such as the content of phenolic glycosides and the β-glucosidase activity present in the olive fruit. The phenolic compositions of VOO from two olive cultivars, Arbequina and Picual, were studied throughout the ...
Romero-Segura, Carmen   +4 more
openaire   +2 more sources

Development of inhibitors against lipase and α-glucosidase from derivatives of monascus pigment

FEMS Microbiology Letters, 2007
New derivatives of monascus pigment were produced during Monascus fermentation by the addition of unnatural amino acids, and the inhibitory activities of the derivatives against diet-related lipase and alpha-glucosidase were tested. Derivatives with penicillamine (H-Pen), cyclohexylalanine (H-Cha), butylglycine (L-t-Bg), and norleucine (H-Nle) showed ...
Jong Hoon, Kim   +5 more
openaire   +2 more sources

Induction and preliminary characterization of intracellular β-glucosidases from a cellulolyticStreptomycesstrain

FEMS Microbiology Letters, 1995
The cellulolytic actinomycete Streptomyces sp. QM-B814 possess an intracellular beta-glucosidase system which is induced by cellobiose and carboxymethylcellulose. Maximal beta-glucosidase activity was attained 8-10 h after inducer addition to exponential phase growing cultures. The induction is depressed in the presence of glucose.
J A, Pérez-Pons   +2 more
openaire   +2 more sources

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