Results 101 to 110 of about 89,329 (241)
Advanced Healthcare Materials, EarlyView.The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang +13 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.A multilayered small‐caliber vascular scaffold combining electrospinning and 4‐axis printing is developed and biofunctionalized with marine sulfated polysaccharides from Holothuria tubulosa. The resulting construct exhibits enhanced hemocompatibility, tunable mechanical properties, and supports endothelial and smooth muscle cell adhesion and ...
Gabriele Obino +9 more
wiley +1 more source
NF-κB signaling and crosstalk during carcinogenesis
4 open, 2019 Transcription factors (TFs) are proteins that control the transcription of genetic information from DNA to mRNA by binding to specific DNA sequences either on their own or with other proteins as a complex.
Brücher Björn L.D.M. +2 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Platform system to create biofabricated 3D spinal cord tissue models: Combining high resolution PCL fiber placement, a customized, hyaluronic acid‐based hydrogel, two cell types (spinal cord neurons and astrocytes) together with three distinct laminin isoforms allow the formation of functional cell–cell network interactions.
Nicoletta Murenu +12 more
wiley +1 more source
SRM Journal of Research in Dental Sciences, 2014 Introduction: Oral submucous fibrosis (OSMF) is a chronic debilitating disease and a premalignant condition of the oral cavity characterized by generalized submucosal fibrosis with a multifactorial etiology.
Teena Philip +5 more
doaj +1 more source
The role of Sox9 in mouse mammary gland development and maintenance of mammary stem and luminal progenitor cells. [PDF]
, 2014 BackgroundIdentification and characterization of molecular controls that regulate mammary stem and progenitor cell homeostasis are critical to our understanding of normal mammary gland development and its pathology.ResultsWe demonstrate that conditional ...
Band, Hamid +7 more
core +2 more sources
Probing Cellular Activity Via Charge‐Sensitive Quantum Nanoprobes
Advanced Materials, EarlyView.A new quantum sensing modality detects shifts in zero‐field splitting caused by charge rearrangement with diamond nanocrystals in response to cellular activity. These electric‐field‐driven effects provide an alternative to temperature‐based interpretations, enabling real‐time, single‐cell readout of inflammation.
Uri Zvi +16 more
wiley +1 more source
Exosomes promote pre-metastatic niche formation in ovarian cancer. [PDF]
, 2019 Ovarian cancer is one of the most common gynecological malignancies. Upon initial diagnosis, the majority of patients present with widespread metastatic growth within the peritoneal cavity. This metastatic growth occurs in stages, with the formation of a
Dean, Dylan C +4 more
core +2 more sources
Advanced Materials, EarlyView.To enhance stability and long‐term biocompatibility of wearable microneedle sensors, a crosslinking‐recombination bovine serum albumin material is used as a buffer layer coated on microneedle sensors. This coating layer possesses a unique stiff‐to‐soft transition function balancing the mechanical stiffness desired for puncturing and soft required for ...
Lihao Guo +16 more
wiley +1 more source
FFNT25 ameliorates unilateral ureteral obstruction-induced renal fibrosis
Renal Failure, 2019 Renal fibrosis is a common pathological feature of chronic kidney disease (CKD) patients who progress to end-stage renal disease (ESRD). With the increasing incidence of CKD, it is of importance to develop effective therapies that blunt development of ...
Wen Li +8 more
doaj +1 more source