α-Smooth muscle actin expression in cancerassociated fibroblasts in canine epithelial tumors [PDF]
, 2017 Tumor tissues contain not only cancer cells but also other cell types including, fibroblasts, immune cells, and endothelial cells, which interact with cancer cells.
Hoshino, Yuki +3 more
core +1 more source
Novel Omega-3 Fatty Acid Epoxygenase Metabolite Reduces Kidney Fibrosis. [PDF]
, 2016 Cytochrome P450 (CYP) monooxygenases epoxidize the omega-3 polyunsaturated fatty acid (PUFA) docosahexaenoic acid into novel epoxydocosapentaenoic acids (EDPs) that have multiple biological actions.
Hammock, Bruce D +5 more
core +3 more sources
Respiratory Research, 2007 Background Epithelial to mesenchymal transition (EMT) in alveolar epithelial cells (AECs) has been widely observed in patients suffering interstitial pulmonary fibrosis.
Yang Xiao +6 more
doaj +1 more source
Specialized mouse embryonic stem cells for studying vascular development. [PDF]
, 2014 Vascular progenitor cells are desirable in a variety of therapeutic strategies; however, the lineage commitment of endothelial and smooth muscle cell from a common progenitor is not well-understood.
Burns, Andrew B +5 more
core +1 more source
Effect and mechanism of TGF-β on macrophage-derived cancer-associated fibroblasts in bladder can-cer tissue [PDF]
精准医学杂志Objective To investigate the effect and mechanism of TGF-β on macrophage-derived cancer-associated fibroblasts (CAFs) in bladder cancer tissue. Methods The Kaplan-Meier method was used to investigate the relationship between the expression of α-SMA+CD68 ...
PU Shi, SHEN Chengquan, HU Ding, ZHAO Xinzhao, QIN Ruize, LIU Changxue, WANG Yonghua
doaj +1 more source
Deletion of EP4 in S100a4-lineage cells reduces scar tissue formation during early but not later stages of tendon healing [PDF]
, 2017 Tendon injuries heal via scar tissue rather than regeneration. This healing response forms adhesions between the flexor tendons in the hand and surrounding tissues, resulting in impaired range of motion and hand function.
Ackerman, Jessica E +3 more
core +2 more sources
Phenotypic characterization of human prostatic stromal cells in primary cultures derived from human tissue samples [PDF]
, 2013 Emerging evidence has shown that the tumor microenvironment plays a crucial role in prostate cancer (PCa) development and progression. However, the mechanism(s) through which stromal cells regulate epithelial cells and the differences among prostatic ...
Clemente, Luigi Di +7 more
core +1 more source
Immunohistochemical analysis of α-SMA and GFAP expression in liver stellate cells [PDF]
Vojnosanitetski Pregled, 2006 Background/Aim. Liver stellate cells play an important role in hepatic fibrosis, and its progression to cirrhosis. These cells show immunoreactivity with different monoclonal antibodies amongst which the commonest are α-smooth muscle actin (α-SMA) and ...
Tomanović Nada +2 more
doaj +1 more source
RRx-001, an epigenetic-based radio- and chemosensitizer, has vascular normalizing effects on SCCVII and U87 tumors. [PDF]
, 2016 BackgroundThe tumor-specific microregional effects of the anticancer agent RRx-001, a novel epigenetic-based radio/chemosensitizer with nitrogen oxide-donating properties in phase II clinical trials, were investigated with whole tissue section ...
Cabrales, Pedro +3 more
core +2 more sources
Indian Journal of Pathology and Microbiology, 2018 Background and Objectives: Myoepithelial cells (ME) are known to contribute in the patterning of salivary gland neoplasms (SGN) and possess cytoplasmic smooth muscle actin (SMA) revealed by alpha SMA (α-SMA).
Mahalakshmi Ravi +5 more
doaj +1 more source