Results 231 to 240 of about 89,329 (241)

Retinal ischemia induces α-SMA-mediated capillary pericyte contraction coincident with perivascular glycogen depletion. [PDF]

Acta Neuropathol Commun, 2019
Alarcon-Martinez L, Yilmaz-Ozcan S, Yemisci M, Schallek J, Kılıç K, Villafranca-Baughman D, Can A, Di Polo A, Dalkara T.   +8 more
europepmc   +1 more source

Intratumoral Fusobacterium nucleatum Drives Cancer‐Associated Fibroblasts Enrichment and Immune Exclusion in Esophageal Squamous Cell Carcinoma

Annals of Gastroenterological Surgery, EarlyView.
Fusobacterium nucleatum contributes to the progression of ESCC by inducing NF‐κB–mediated inflammatory signaling in tumor cells and promoting CAFs activation. Its presence may facilitate immune exclusion and tumor invasion through stromal remodeling. Furthermore, F.
Takashi Ofuchi, Qingjiang Hu, Kazuki Omachi, Kosuke Kanemitsu, Hajime Otsu, Yusuke Yonemura, Taro Tobo, Yoshifumi Baba, Masaaki Iwatsuki, Koshi Mimori   +9 more
wiley   +1 more source

A Soft‐Tip Hydraulically Steerable Catheter for Enhanced Flexibility and Safety in Vascular Interventions

Advanced Intelligent Systems, EarlyView.
This study introduces a hydraulically steerable catheter with a soft tip in vascular procedures. The steering soft tip achieves a minimal diameter of 2.6 mm and supports a 180° bend. Real‐time shape and position tracking, facilitated by segmentation and endpoint detection techniques, improves navigation.
Jingyi Kang, Ye Wang, Jiayuan Liu, Zhuhao Wang, Xuan Yang, Jie Wang, Jian Wu, Guochen Ning, Boyu Zhang, Hongen Liao   +9 more
wiley   +1 more source

From Origami to Bistable and Laminate Structures: A Review for Multifunctional Applications from Structural Perspective of Shape‐Changing Structures

Advanced Intelligent Systems, EarlyView.
This review explores how shape‐changing structures—origami, bistable, and laminate structures—enable multifunctionality in soft robotics and metamaterials. Starting from structural design, it examines core principles, real‐world applications, and ongoing challenges.
Lingchen Kong, Yaoyao Fiona Zhao
wiley   +1 more source

Sub‐Micrometer‐Precision Path Following of Piezo‐Actuated Mobile Robot

Advanced Intelligent Systems, EarlyView.
This article reports on the Holonomic‐Beetle (HB), a palm‐sized robot that achieves sub‐micrometer (sub‐µm) precision path tracking across spatial ranges from 100 µm to 10 mm. Using proportional‐integral‐derivative (PID) control, the HB accurately tracks both complex and straight paths with sub‐µm path errors, surpassing existing robots.
Eiji Kusui, Chihiro Sekine, Taiki Goto, Ryosuke Kinoshita, Yuko Nishimura, Shogen Sekiguchi, Satoshi Ando, Yuto Oishi, Yusuke Matsui, Ohmi Fuchiwaki   +9 more
wiley   +1 more source

A Neural Network‐Based Self‐Sensing Embedded Position Control System for Shape Memory Alloy Wire Actuators

Advanced Intelligent Systems, EarlyView.
Shape memory alloy wires exhibit thermally induced phase changes that generate actuation strain and resistance variations enabling self‐sensing. However, hysteretic electromechanical behavior complicates accurate state estimation. This paper presents an artificial in‐based self‐sensing method to reconstruct SMA actuator position in real time, achieving
Krunal Koshiya, Gianluca Rizzello, Paul Motzki   +2 more
wiley   +1 more source

Animal models of benign airway stenosis: Advances in construction techniques, evaluation systems, and perspectives

Animal Models and Experimental Medicine, EarlyView.
Currently, the animals commonly used to establish animal models of benign airway stenosis (BAS) include mice, rats, pigs, dogs, rabbits, and ferrets. The establishment methods involve one or a combination of two methods such as mechanical injury, tracheal cautery, cuff overpressure intubation, laser injury, and endoscopic silver nitrate cauterization ...
Wusheng Zhang, Yilin Chen, Chengcheng Yang, Yuchao Dong, Haidong Huang, Hui Shi, Chong Bai   +6 more
wiley   +1 more source

Quantitative proteomics identifies clusterin as a novel biomarker for atherosclerosis

Animal Models and Experimental Medicine, EarlyView.
This schematic illustrates the proposed mechanism. In advanced atherosclerotic lesions, upregulated CLU on the cell surface activates low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1). This interaction triggers the phosphorylation and activation of AKT.
Dengfeng Ding, Yingjie Zhang, Li Zhang, Xinou Zheng, Miaomiao Niu, Yunxiao Jia, Xuezhuang Li, Hua Chen, Chao Guo, Tao Jiang, Yuqiong Zhao   +10 more
wiley   +1 more source

Mannose‐Modified Cationic Liposome‐Based mRNA Therapeutics for Improved Triple‐Negative Breast Cancer Immunotherapy

Advanced NanoBiomed Research, EarlyView.
Schematic illustration of mTEM8‐loaded cationic liposome (cLipo‐Man/mTEM8) therapeutics for improved triple‐negative breast cancer immunotherapy. Despite triple‐negative breast cancer (TNBC) is the most heterogeneous and aggressive subtype of breast cancer, immunotherapy is emerging as a promising therapy.
Kexin Deng, Juping Sun, Junyu Liu, Yuqi Zhang, Wanwan Liu, Xiaobin Li, Han Wu, Juan Li, Jisong Zhang, Chanyuan Jin, Can Yang Zhang   +10 more
wiley   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source