Intra-Islet Paracrine Regulation of Glucagon Secretion During Hypoglycemia, Euglycemia, and Hyperglycemia. [PDF]
Fatehi S, Rocheleau JV, Riddell MC.
europepmc +1 more source
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Designing an optimized strategy for extracellular expression of recombinant human TNF-α in <i>Escherichia coli</i>. [PDF]
Akanksha +5 more
europepmc +1 more source
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
<i>Clostridioides difficile</i> water-soluble zwitterionic lipoteichoic acid wsPS-III: structure, synthesis, and immunogenicity. [PDF]
Ma Z +11 more
europepmc +1 more source
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Hierarchical exfoliated MoS<sub>2</sub>@Ti<sub>3</sub>C<sub>2</sub>T <sub><i>x</i></sub> @α-Ni(OH)<sub>2</sub> as a highly efficient electrocatalyst for water splitting in acidic medium: experimental and DFT investigations. [PDF]
Upar DA +5 more
europepmc +1 more source

