Results 41 to 50 of about 69,375 (242)
Potential peptidic proteasome inhibitors by incorporation of an electrophilic trap based on amino acid derived α-substituted sulfonyl fluorides [PDF]
, 2017 Peptido sulfonyl fluoride derivatives were designed and synthesized containing a substituent on the alpha position (αPSFs) with respect to the sulfonyl fluoride electrophilic trap.
Brouwer, Arwin J. +3 more
core +1 more source
Recent Advances in the Synthetic and Mechanistic Aspects of the Ruthenium-catalyzed Carbon-heteroatom Bond Forming Reactions of Alkenes and Alkynes [PDF]
, 2011 The group’s recent advances in catalytic carbon-to-heteroatom bond forming reactions of alkenes and alkynes are described. For the C–O bond formation reaction, a well-defined bifunctional ruthenium-amido catalyst has been successfully employed for the ...
Yi, Chae S.
core +2 more sources
Ionic behavior assessment of surface-active compounds from corn steep liquor by exchange resins [PDF]
, 2016 Depending on their ionic nature, biosurfactants can be classified as nonionic, anionic, cationic, or amphoteric. The ionic behavior of biosurfactants is an important characteristic that dictates their use in industrial applications.
Cruz, J. M. +4 more
core +2 more sources
Efficient seeding techniques for protein similarity search [PDF]
, 2008 We apply the concept of subset seeds proposed in [1] to similarity search in protein sequences. The main question studied is the design of efficient seed alphabets to construct seeds with optimal sensitivity/selectivity trade-offs.
Furletova, Eugenia +6 more
core +10 more sources
Synthesis of cis- and trans-3-Aminocyclohexanols by Reduction of β-Enaminoketones
Molecules, 2011 We describe a protocol developed for the preparation of β-enaminoketones derived from 1,3-cyclohexanediones, and their subsequent reduction by sodium in THF-isopropyl alcohol to afford cis- and trans-3-aminocyclohexanols.
Irma Linzaga-Elizalde +4 more
doaj +1 more source
Microwave-assisted regioselective ring opening of non-activated aziridines by lithium aluminium hydride [PDF]
, 2010 A new synthetic protocol for the LiAlH4-promoted reduction of non-activated aziridines under microwave conditions was developed. Thus, ring opening of 2-(acetoxymethyl)aziridines provided the corresponding beta-amino alcohols, which were then used as ...
D'hooghe, Matthias +2 more
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Applied Sciences, 2012 Some chiral β-amino alcohols have been evaluated as potential ligands for the ruthenium-catalyzed asymmetric transfer hydrogenation (ATH) of N-phosphinyl ketimines in isopropyl alcohol. The ruthenium complex prepared from [RuCl2(p-cymene)]2 and (1S,2R)-1-
Óscar Pablo, David Guijarro, Miguel Yus
doaj +1 more source
Food Chemistry: X, 2023 In order to find out the effect of salt concentration on fermented rape stalks, the physicochemical quality and volatile components was investigated using high performance liquid chromatography (HPLC) and headspace solid phase microextraction gas ...
Sijie Zhang +5 more
doaj +1 more source