Results 71 to 80 of about 958,179 (168)

Comorbidity Mechanism and Management of Chronic Low Back Pain and Major Depressive Disorder: From Neural Circuit Remodeling to Precision Medicine

open access: yesBrain and Behavior, Volume 16, Issue 9, September 2026.
ABSTRACT Objective This review systematically elaborates multi‐system interactive mechanisms underlying comorbid chronic low back pain (CLBP) and major depressive disorder (MDD), synthesizes recent advances in diagnosis, treatment, and management, and proposes precision medicine directions to address clinical challenges, including missed diagnosis ...
Lin Faqu   +3 more
wiley   +1 more source

Plasma β-Endorphin, the Menstrual Cycle and Exercise [PDF]

open access: yes, 1988
The underlying mechanism(s) of exercise-associated amenorrhea are not well understood. The discovery of β-endorphin, an endogenous opioid peptide that was shown to inhibit LH release during the menstrual cycle and become elevated during intense exercise,
Harber, Jane Victoria
core   +1 more source

Circulating β-endorphin, adrenocorticotrophic hormone and cortisol levels of stallions before and after short road transport: stress effect of different distances

open access: yesActa Veterinaria Scandinavica, 2008
Background Since transport evokes physiological adjustments that include endocrine responses, the objective of this study was to examine the responses of circulating β-endorphin, adrenocorticotrophic hormone (ACTH) and cortisol levels to transport stress
Grasso Loredana   +4 more
doaj   +1 more source

Smoking Abstinence Elicits Hyperalgesia: Neural Mechanism, Clinical Implications, and Pharmacological Managements

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
The cycle between nicotine use and pain modulation. Cigarette smoking leads to nicotine entering the body, which binds to nicotinic acetylcholine receptors (nAChRs) in the brain, triggering the release of different neurotransmitters, including dopamine (DA), norepinephrine (NE), serotonin (5‐HT), and GABA.
Shan‐shan Hu   +3 more
wiley   +1 more source

Peroxisomal Localization of the Proopiomelanocortin-Derived Peptides β-Lipotropin and β-Endorphin

open access: yes, 2010
The peptide hormones ACTH, MSHs, β-lipotropin (β-LPH), and β-endorphin are all derived from the precursor molecule proopiomelanocortin (POMC). Using confocal laser microscopy and immunoelectron microscopy in human pituitary gland, we demonstrate a ...
Sonja Forss-Petter   +11 more
core   +1 more source

Ethanol-activated microglial exosomes induce MCP1 signaling mediated death of stress-regulatory proopiomelanocortin neurons in the developing hypothalamus

open access: yesJournal of Neuroinflammation
Background Microglia, a type of resident immune cells within the central nervous system, have been implicated in ethanol-activated neuronal death of the stress regulatory proopiomelanocortin (POMC) neuron-producing β-endorphin peptides in the ...
Prashant Tarale   +3 more
doaj   +1 more source

Associations Between Prayer Practices, Healthy Behaviors, and Depression Among Iranian Medical Students: A Cross‐Sectional Structural Equation Modeling Study

open access: yesHealth Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Prayer is a concept that indicates the level of an individual's commitment, attachment, and adherence to worship in life. However, evidence regarding its associations with health behaviors and depression remains limited. This study aimed to examine the associations between prayer practices, healthy behaviors, and depression among ...
Mehrdad Karimi   +3 more
wiley   +1 more source

Plasma and red blood cell β-endorphin immunoreactivity in normal and complicated pregnancies: Gestational age variation

open access: yes, 1985
Recent observations suggest that there may be two pools of β-endorphin-like immunoreactivity in mammalian circulation. One of these pools is present in plasma and the other is detected in association with erythroyctes.
Robichaux, A. G.   +6 more
core   +1 more source

Effect of combined acupuncture-medicine anesthesia in thyroid nodule ablation and its effect on serum β-endorphin

open access: yes针刺研究, 2020
Objective To investigate the anesthetic effect of combined acupuncture-medicine anesthesia in microwave ablation of benign thyroid nodules and its effect on serum β-endorphin.
YANG Xiao-ying   +6 more
doaj   +2 more sources

Alterations in brain dopamine and serotonin metabolism during the development of tolerance to human β-endorphin in rats

open access: yes, 1978
Repeated intracisternal injections of human β-endorphin lead to development of tolerance with respect to the catalepsy, analgesia, and hypothermia which are seen following a single injection.
Errol B. De Souza   +2 more
core   +1 more source

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