Results 61 to 70 of about 958,179 (168)

Opioid Modulation of Major Neurotransmitter Systems: Acute, Chronic, and Withdrawal Effects

European Journal of Neuroscience, Volume 64, Issue 9, November 2026.
Opioids are widely used but also frequently misused drugs that affect multiple neurotransmitter systems, including dopaminergic, glutamatergic, GABAergic, serotonergic, and cholinergic pathways. Opioid‐induced neuroadaptations depend on the duration of drug exposure, with distinct changes also emerging following drug discontinuation.
Daniela Novakova, Eliska Pritulova, Jiri Novotny   +2 more
wiley   +1 more source

Detection of two endorphin-like peptides in nucleus caudatus

, 1978
Two endorphin-like peptides with molecular weight larger than [met5]-enkephaiin were detected in bovine caudate. They were separated from [met5]-enkephal in by Biogel P-2 column chromatography and detected with a [met5]-enkephaiin antibody which ...
E. Costa, W. Fratta, H. T. T. Yang, J. S. Hong, A.M. Di Giulio   +4 more
core   +1 more source

Step into action: how reminders shape engagement in fitness apps

Economica, Volume 93, Issue 372, Page 1225-1259, October 2026.
Abstract Regular exercise offers well‐documented health benefits, and mobile applications are increasingly used to promote physical activity. In this study, we conduct a large‐scale randomized controlled trial with 20,187 users of the WeWard app in France to evaluate the effectiveness of different message framings and intervention durations on app ...
Beatrice Braut, Claire Mollier, Sarah Zaccagni   +2 more
wiley   +1 more source

Estrogen modulation of two subpopulations of β-endorphin neurons in ovariectomized guinea pigs distinguished by peripherally injected fluorogold

, 1995
β-endorphin released by neurons in the arcuate nucleus affects the output of several neuroendocrine systems and estrogen levels modulate the production and secretion of β-endorphin.
Nguyen, Thao T., Thornton, Janice E., Loose, Michael D., Niu, Joan C.   +3 more
core   +1 more source

The Skin‐Lightening Efficacy and Mechanisms of Botanical Extracts: A Comprehensive Review

Journal of Cosmetic Dermatology, Volume 25, Issue 10, October 2026.
ABSTRACT Background Skin pigmentation is regulated by a complex network involving melanogenesis, melanosome transfer, oxidative stress, environmental stimuli, and epidermal turnover. Botanical extracts and phytochemicals have attracted increasing interest as potential skin‐lightening agents. This review evaluates their efficacy, mechanisms, and safety.
Siting Yang, Mingning Ding, Chenglong Ye, Jingning Shen, Lihua Zhang, Anquan Yang, Lihao Gu   +6 more
wiley   +1 more source

Dynamic Β-endorphin determination in hematologic patients

Терапевтический архив, 2012
Aim. To perform a dynamic study of Β-endorphin, hypoxia-inducible factor-1α (HIF-1α), and cytokines in hematologic patients. Subjects and methods. Fifty-nine patients with different types of acute leukemia (AL), 30 with anaplastic anemia (AA), 24 with ...
A B Makeshova, Iu I Mamukova, A A Levina, E P Sysoeva, M O Éralieva, V G Savchenko   +5 more
doaj  

Effects of β-endorphin on plasma glucose levels

, 2010
Healthy, and insulin-deficient (streptozotocin-induced diabetic, STZ) Sprague-Dawley rats were used to investigate the effects of different doses of β-endorphin (25 and 50 μg/kg) on plasma β-endorphin, insulin, glucagon, and glucose levels at 15- and 30 ...
Akalin, PINAR, Baspinar, Nuri
core   +1 more source

β-Endorphin: lack of correlation between opiate activity and immunoreactivity by radioimmunoassay

, 1977
A sensitive radioimmunoassay for human β-endorphin has been developed. When natural human β-lipotropin and various synthetic analogs of β-endorphin were assayed for their immunoreactivity, lack of correlation was found between opiate activity and ...
Li, Choh Hao, Jagannadha Rao, A., Doneen, Byron A., Yamashiro, Donald   +3 more
core   +1 more source

Exercise prevents high-fat diet-induced hyperalgesia in rats: an in vivo microdialysis study [PDF]

Arquivo Brasileiro de Medicina Veterinária e Zootecnia
In this study, we investigated pain threshold and β-endorphin concentration in both sedentary and exercise trained rats under high fat diet induced obesity.
M. Seyran, A. Gündoğdu, Y.G. Özkaya
doaj   +2 more sources

TRPV4/NCX1 coupling regulates Ca2+‐dependent cholecystokinin secretion from enteroendocrine cells to involve the pathogenesis of irritable bowel syndrome‐diarrhea in male mice

Physiological Reports, Volume 14, Issue 20, October 2026.
ACh regulates the increase of intracellular Ca2+ signaling through TRPV4/NCX1 coupling, inducing CCK release, and participates in the pathogenesis of IBS‐D. Abstract Although stress can stimulate the vagus nerve via the brain–gut axis to induce enterohormone secretion from enteroendocrine cells (EECs), little is currently known about the roles of ion ...
Jianxin Wang, Xiongying Chen, Shuo Tong, Chengxin Qu, Wei Lu, Hui Dong   +5 more
wiley   +1 more source