Results 41 to 50 of about 958,179 (168)

Expression of β-endorphin in spleen tissue sections.

, 2013
Immunohistochemical staining of β-endorphin positive cells in rat splenic tissues from EAE and EA rats 14 days post immunization. (A) β-endorphin positive cells in EAE rats. (B) β-endorphin positive cells in EA rats. Magnification: ×100.
Jinghua Wang (101820), Dandan Wang (286632), Bo Sun (177052), Jinfeng Yang (286633), Guangyou Wang (286635), Hulun Li (286636), Qingfei Kong (286631), Yao Zhang (134381), Lili Mu (286630), Mingyan Zhou (286634), Xinyue Wang (286629), Yumei Liu (286628), Hongwei Wang (151141)   +12 more
core   +1 more source

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

British Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux, Solenn Gousset, Beltrán Alvarez, Monica Baiula, Wouter Bakker, Andrea Bedini, Monir Bertayli, Divakar Budda, Robert Carr, Elisabetta Cuna, Óscar Díaz, Nina Donner, Jesús Giraldo, Geert‐Jan Groeneveld, Berfin Gülave, David Guydan, Hemme Hijma, Rafael Maldonado, Pedro Renault, Carlos Rinaudo, Jeroen Elaissaiss‐Schaap, Athan Spiros, Sara Stoeber, Petri Takkala, Daan van Valkengoed, Coen van Hasselt, Elizabeth (Liesbeth) C.M. de Lange   +26 more
wiley   +1 more source

Gut microbiota as a novel therapeutic target for eating disorders and obesity

British Journal of Pharmacology, EarlyView.
The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė, Victor Mathis, Emmanuel Darcq, Aurelijus Burokas, Elena Martín‐García, Rafael Maldonado   +5 more
wiley   +1 more source

β-Endorphin biotransformation in brain: Formation of γ-endorphin by a synaptosomal plasma membrane associated endopeptidase distinct from cathepsin D [PDF]

, 1980
cSPM preparations of rat brain contain a peptidase activity which generates γ-endorphin from β-endorphin. Some properties of this enzyme were studied and compared with those of cathepsin D.
Verhoef, J., Loeber, J.G., Burbach, J.P.H., Kloet, E.R. de   +3 more
core  

Influence of Beta-Endorphin on Oxygen Activity of Neutrophils and Total Antioxidant Status in Rats after Chronic Administration of Methimazole

Journal of Veterinary Research, 2013
The aim of the study was to evaluate the effect of β-endorphin on oxygen activity of polimorphonuclear neutrophils and to investigate the total antioxidant status of blood serum in rats subjected to chronic treatment with methimazole.
Gołyński Marcin, Lutnicki Krzysztof
doaj   +1 more source

Innovation relaxation belts to reduce labor pain itensity and increase β-endoprhine levels

Medisains, 2020
Background: Labor pain feels tremendous, and only 2-4% of mothers low pain during labor. Heat therapy is a non-pharmacological method. The heat therapy is still conventional, and this study uses a relaxation belt with more stable, dry heat media, and ...
Candra Tyas Nur Fitria, Runjati Runjati, Sutopo Patriajati, Choiroel Anwar   +3 more
doaj   +1 more source

GLP‐1 receptor activation attenuates chronic migraine‐like behaviour: Sex‐specific modulation of opioid‐ and endocannabinoid‐related pathways

British Journal of Pharmacology, EarlyView.
Background and Purpose Chronic migraine (CM) is a highly disabling condition that remains suboptimally treated. Metabolic disturbances may trigger migraine chronification, whereas impaired endogenous pain inhibition contributes to CM development. Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs), used for type 2 diabetes and obesity, show efficacy ...
Katarina Sićović, Katarina Nastić, Miroslav Dinić, Emilija Brdarić, Uroš Pecikoza, Maja Tomić, Ana Micov   +6 more
wiley   +1 more source

Naltrexone Protects Against Hypotension, Hyperthermia, and β-Endorphin Overproduction During Heatstroke in the Rat

Journal of Pharmacological Sciences, 2005
Heat stroke is characterized by hyperthermia, arterial hypotension, decreased baroreflex sensitivity, and increased serum levels of β-endorphin. Whereas naltrexone may have therapeutic potential in heat stroke, the underlying mechanism remains unclear ...
Yi-Ping Huang, Mao-Tsun Lin, Jwo-Sheng Chen, Pang-Yen Wu   +3 more
doaj   +1 more source

Perceived headache responses to exercise in patients with migraine: A cross‐sectional study

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To characterize patient‐perceived headache responses to exercise in migraine and to identify associated clinical factors using a large‐scale registry. Background Regular exercise is often recommended for patients with migraine; however, it can also trigger migraine attacks.
Young‐Eun Gil, Mi Ji Lee
wiley   +1 more source

Blue light (λ=453 nm) nitric oxide dependently induces β-endorphin production of human skin keratinocytes in-vitro and increases systemic β-endorphin levels in humans in-vivo [PDF]

, 2019
β-Endorphin exerts a broad spectrum of physiological activity on mood, immune functions, pain management, reward effects, and behavioral stability. β-Endorphin is produced in certain neurons within the central and peripheral nervous system but also in ...
Albers, Isabel, Broja, Melanie, Windolf, Joachim, Zernickel, Erika, Grotheer, Vera, Stern, Manuel, Hans Lucas, Busch, Heiss, Christian, Suschek, Christoph V.   +8 more
core   +1 more source