Results 21 to 30 of about 9,951 (130)
Indonesian Biomedical Journal, 2012 BACKGROUND: β-endorphin plays a role in the descending pain control in the central nervous system. Central sensitization may be involved in the generating and maintenance of osteoarthritis (OA) pain.
Hori Hariyanto +4 more
doaj +1 more source
Neuropsychopharmacology Reports, 2023 Aim We aimed to compare neuropeptide levels between patients with major psychiatric disorders and healthy controls and examine their association with symptoms and cognitive function.
Shinsuke Hidese +5 more
doaj +1 more source
PECULIARITIES OF CHRONIC PAIN AND PAIN-RELATED STRESS MARKERS IN PRETERM INFANTS
Неонатологія, хірургія та перинатальна медицина, 2023 Preterm infants are a special cohort of newborns that require long-term treatment in the neonatal intensive care unit (NICU). NICU stay, accompanied by numerous excessive stimuli, painful procedures, and separation from parents leads to a high risk of ...
Г. Павлишин +3 more
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Redox Biology, 2020 The prevalence of chronic widespread pain (CWP) in people with HIV is high, yet the underlying mechanisms are elusive. Leukocytes synthesize the endogenous opioid, β-endorphin, within their endoplasmic reticulum (ER).
Saurabh Aggarwal +9 more
doaj +1 more source
An opponent process for alcohol addiction based on changes in endocrine gland mass
iScience, 2021 Summary: Consuming addictive drugs is often initially pleasurable, but escalating drug intake eventually recruits physiological anti-reward systems called opponent processes that cause tolerance and withdrawal symptoms. Opponent processes are fundamental
Omer Karin, Moriya Raz, Uri Alon
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Innovation relaxation belts to reduce labor pain itensity and increase β-endoprhine levels
Medisains, 2020 Background: Labor pain feels tremendous, and only 2-4% of mothers low pain during labor. Heat therapy is a non-pharmacological method. The heat therapy is still conventional, and this study uses a relaxation belt with more stable, dry heat media, and ...
Candra Tyas Nur Fitria +3 more
doaj +1 more source
Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?
British Journal of Pharmacology, EarlyView.Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli +7 more
wiley +1 more source
Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux +26 more
wiley +1 more source
Journal of Veterinary Research, 2013 The aim of the study was to evaluate the effect of β-endorphin on oxygen activity of polimorphonuclear neutrophils and to investigate the total antioxidant status of blood serum in rats subjected to chronic treatment with methimazole.
Gołyński Marcin, Lutnicki Krzysztof
doaj +1 more source