β-endorphin suppresses ultraviolet B irradiation-induced epidermal barrier damage by regulating inflammation-dependent mTORC1 signaling [PDF]
Scientific Reports, 2023 Solar ultraviolet B (UVB) radiation triggers excessive inflammation, disrupting the epidermal barrier, and can eventually cause skin cancer. A previous study reported that under UVB irradiation, epidermal keratinocytes synthesize the proopiomelanocortin ...
Hyung-Su Kim +4 more
doaj +2 more sources
IL-10/β-Endorphin-Mediated Neuroimmune Modulation on Microglia during Antinociception [PDF]
Brain Sciences, 2023 Microglia are glial cells centrally related to pathophysiology and neuroimmunological regulation of pain through microglia–neuron crosstalk mechanisms. In contrast, anti-inflammatory mechanisms guided by immunological effectors such as IL-10 trigger the ...
Thiago Caetano Andrade Belo +7 more
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β-Endorphin (an endogenous opioid) inhibits inflammation, oxidative stress and apoptosis via Nrf-2 in asthmatic murine model [PDF]
Scientific Reports, 2023 Asthma, a chronic respiratory disease is characterized by airway inflammation, remodelling, airflow limitation and hyperresponsiveness. At present, it is considered as an umbrella diagnosis consisting several variable clinical presentations (phenotypes ...
Vinita Pandey +4 more
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Cynandione A Alleviates Neuropathic Pain Through α7-nAChR-Dependent IL-10/β-Endorphin Signaling Complexes [PDF]
Frontiers in Pharmacology, 2021 Cynandione A, an acetophenone isolated from Cynanchum Wilfordii Radix, exhibits antineuropathic pain effect. This study further explored the target molecule and signaling mechanisms underlying cynandione-A-induced antineuropathic pain.
Qiao-Qiao Han +5 more
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Circulating levels of β-endorphin and cortisol in breast cancer [PDF]
Comprehensive Psychoneuroendocrinology, 2021 Neurobehavioral stress can promote the growth and progression of different types of cancer because psychological factors can alter immune and endocrine function.
María Jesús Ramírez-Expósito +4 more
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Cannabinoid CB2 Receptors Contribute to Upregulation of β-endorphin in Inflamed Skin Tissues by Electroacupuncture [PDF]
Molecular Pain, 2011 Background Electroacupuncture (EA) can produce analgesia by increasing the β-endorphin level and activation of peripheral μ-opioid receptors in inflamed tissues.
Su Tang-feng +8 more
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Effects of Pulsed Radiofrequency Current and Thermal Condition on the Expression of β-Endorphin in Human Monocytic Cells [PDF]
NeuroSciPulsed radiofrequency (PRF) current applied to peripheral nerves is a modality used in interventional pain medicine, but its underlying mechanisms remain unclear.
Akira Nishioka +3 more
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COMT gene variants and β-endorphin levels contribute to ethnic differences in experimental pain sensitivity [PDF]
Molecular Pain, 2020 This cross-sectional study investigated whether the catechol-O-methyltransferase (COMT) gene acts as a significant regulator of pain signaling pathways, regulates β-endorphin, and contributes to ethnic differences in pain sensitivity.
Feng Xu +12 more
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β-Endorphin Mediates the Development and Instability of Atherosclerotic Plaques [PDF]
International Journal of Endocrinology, 2020 β-Endorphin, an endogenous opioid peptide, and its μ-opioid receptor are expressed in brain, liver, and peripheral tissues. β-Endorphin induces endothelial dysfunction and is related to insulin resistance.
Taisuke Okano +10 more
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Pain Relief Dependent on IL-17–CD4+ T Cell–β-Endorphin Axis in Rat Model of Brachial Plexus Root Avulsion After Electroacupuncture Therapy [PDF]
Frontiers in Neuroscience, 2021 Background and purposeNeuropathic pain is the typical symptom of brachial plexus root avulsion (BPRA), and no effective therapy is currently available.
Zihang Xu +17 more
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